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Thursday, Aug 28, 2008
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  • Highlights of a new position statement on hormone therapy



    The position statement evaluates the risk-benefit ratio of perimenopausal and postmenopausal estrogen therapy and estrogen-progestogen therapy for treatment of menopause-related symptoms and disease prevention.

    The role of DPP-4 inhibitors in type 2 diabetes



    Dipeptidyl peptidase-4 inhibitors are useful as add-on therapy for type 2 diabetes not optimally controlled on metformin and/or a thiazolidenedione and may be an alternative to a sulfonylurea. The lack of long-term safety and efficacy data and the relatively high cost of these drugs represent major limitations.

    The role of DPP-4 inhibitors in type 2 diabetes



    Dipeptidyl peptidase-4 inhibitors are useful as add-on therapy for type 2 diabetes not optimally controlled on metformin and/or a thiazolidenedione and may be an alternative to a sulfonylurea. The lack of long-term safety and efficacy data and the relatively high cost of these drugs represent major limitations.

    Common questions physicians may have about emergency contraception


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    Key information about providing emergency contraception




    Making emergency contraception available is not harmful, does not discourage other contraceptive use, and may prevent the physical, psychological, and medical consequences of unintended pregnancy.

    Managing preoperative medications



    Should a particular drug be continued during the perioperative period? When the answer is not clearly Yes, the relative risks and benefits of the medication for an individual patient must be evaluated. Here are some guideposts for sound clinical decisions.

    Efficient use of bridge anticoagulation therapy



    The use of bridge therapy in patients on chronic oral anticoagulation who are undergoing surgery or another invasive procedure needs to be evaluated on a case-by-case basis. Though bridging with low-dose unfractionated heparin is the current standard, low molecular weight heparin appears to be as safe and effective—and much simpler and less expensive to use.

    A history of the black box warning for antidepressants


    Minimizing risk in antidepressant therapy in children and adolescents



    The risk of morbidity and mortality for depressed and anxious children is far greater than that of developing suicidal ideation. The guidelines presented here are designed to help you provide intervention in children who may otherwise have no access to treatment for psychiatric disorders.

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