New and effective drugs are available to combat the growing type 2 diabetes epidemic. However, new drugs are giving rise to new questions for which there are no easy answers.
For example, should lower-risk patients get drugs with proven cardiovascular (CV) benefits, or should these agents be reserved for those with established CV disease? Does the efficacy of the new treatments justify their cost? How aggressively should glycemic goals be pursued – and how ambitious should those goals be in the first place?
Patient Care recently spoke with William H. Herman, MD, MPH, the Stefan S. Fajans/GlaxoSmithKline Professor of Diabetes and Director of the Michigan Diabetes Research and Training Center, University of Michigan, Ann Arbor, to discuss the latest controversies with new diabetes drugs, clinical trials, and guidelines.
“We have a lot of different medications now available, and we have data on for whom they seem to be most effective,” says Herman, who spoke on these unresolved questions at the ACP Internal Medicine Meeting 2018 in New Orleans, Louisiana. “I think the main issue is to personalize treatment according to each individual patient's needs, both with respect to target levels of glycemia and to the choice of agents.”
Key Question 1: Which drugs should we give?
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