Daily Sugared Drink Consumption May Increase Risk of Hepatic Morbidity, Mortality in Older Women
Postmenopausal women who consumed 1 or more sugary drinks daily had a nearly 2-fold increased risk of liver cancer in a study of more than 98 000.
Prescription "Weight Loss" Drugs: Americans Voice an Opinion
Most Americans are aware of the hot prescription drugs associated with weight loss and many are interested in using them. But access and administration are problematic.
Antiobesity Medication Semaglutide 2.4 mg Reduced Risk of MACE by 20%: Topline Results from Landmark SELECT Trial
The reduction in risk of CV events, the first to be shown by an antiobesity drug, was higher than expected and could help alter perceptions of the agents as "lifestyle drugs."
For Accurate BP Measurement, Cuff Size Must Be "Just Right"
Blood pressure cuffs that are too large or too small for an individual's upper arm return measurements that may misguide therapeutic decisions, say study authors.
Atogepant Reduces Monthly Migraine Days vs Placebo in Persons with Chronic Migraine
The oral gepant reduced monthly migraine days as well as mean monthly use of migraine rescue medication.
Start CRC Screening When? Statigenarians, ETOH and HTN, +2: The Five for Friday
ACP CRC first screening age questioned; elders over age 75 years respond better to statins; 1 drink/day ups risk for HTN; OTC lifesaver #2; plus a triple virus assay.
The Moderna mRNA COVID-19 Vaccine May Be Safer in Older Adults than the Pfizer Shot, New Study Suggests
The only head-to-head trial of mRNA COVID-19 vaccine safety in older adults finds one has a slight edge over the other, which might just be enough for some patients.
Merck's 21-Valent Adult Pneumococcal Vaccine Meets Key Endpoints in Pair of Phase 3 Trials
Statistically significant positive immune responses were observed in both vaccine-naive adults and those previously vaccinated, including for the vaccine's 8 unique serotypes.
FDA Grants 501(k) Clearance to Triple Assay for Influenza, RSV, and COVID-19
The triple assay can identify and differentiate influenza, COVID-19, and respiratory syncytial virus in approximately 2 hours and is already in use.
Influenza Vaccination 2023-2024: ACIP Recommendations and Changes
ACIP guidance on influenza vaccination for the 2023-2024 respiratory virus season includes updates important for primary care clinicians.
ACP Updates Guidance on Screening for Colorectal Cancer, Maintains Age 50 Years to Start
The American College of Physicians in the updated guidance maintains the risk/benefit ratio supports screening initiation at age 50 (vs 45) years.
The Primary Care-PM&R Collaboration Can Help Keep Patients Out of the OR
His relationship with primary care physicians is one of the most important, says physiatrist DJ Kennedy, MD, and he lists the reasons in this interview.
Drinking Even 1 Alcoholic Beverage per Day May Increase Risk for Hypertension, Study Finds
The association between ETOH consumption and hypertension among 19 500 healthy adults was "direct and linear," a new dose-response meta-analysis found.
US Albuminuria Testing Far Below Levels Essential for Effective CKD Treatment
Among persons with hypertension and T2D with albuminuria, nearly two-thirds currently go undetected, a significant barrier to diagnosis and treatment of CKD.
New Technologies Will Propel Novel Approaches in PM&R, says AAPM&R President-Elect
Physiatrist DJ Kennedy, MD, is excited by the potential for new, and even existing technology, to present novel options for diagnosis, monitoring, and treatment.
Mean Weight Loss with Tirzepatide Reaches 26% Across 2 Pivotal Phase 3 Clinical Trials
In adults with obesity or overweight plus comorbidities but without T2D once-weekly tirzepatide was associated with significant and durable weight loss vs placebo.
A no-go for aspirin, Vegetarian victory, Opioids and dementia +2: The Five for Friday
No aspirin for healthy elders, Vegan diets vs CVD, Opioids deadly in dementia, plus BP patterns in babies, and the fear of Alzheimer's runs deep.
Daily Dose: Death Often Follows First Opioid After Dementia Dx
A daily dose of clinical news on Patient Care you may have missed.
Low-Dose Aspirin Increases Risk of Bleeding but Does Not Reduce Risk of a First Stroke in Older Adults
A new analysis of the ASPREE trial of aspirin for primary prevention in older adults finds a poor risk-benefit ratio for prevention of stroke.
Cognitive Screening in Older Adults: How they Perceive the Benefits, What they Fear Most
A majority of older adults agree that all aged ≥65 years should be screened annually for dementia; more than half significantly fear a positive result, the National Poll on Healthy Aging reports.
Vegetarian Diet May Augment Effects of Optimal Drug Therapy in Patients at High Risk of CVD
Reductions in LDL-C, HbA1c, and body weight were associated with a variety of vegetarian diets in participants with or at high risk for cardiovascular disease.
Daily Dose: Persistent Opioid Use Post-Hysterectomy
A daily dose of clinical news you may have missed.
Social Determinants of Health and Prevention of Cardiovascular Disease
Methods proven to prevent ASCVD may fall short in certain populations if the impacts of SDOH are not closely monitored. The ACC/AHA provide considerations for 7 health domains.
The Best Referrals to PM&R for Back Pain are the Early Ones, says AAPM&R President-Elect DJ Kennedy, MD
When is a primary care patient with back pain ready for referral to PM&R? No formulas available but basic principles hold true and earlier is always better.
Daily Dose: Care for Acute Stroke in Women Less Urgent
Large US Study Suggests Numbers Needed to Vaccinate to Prevent COVID-19 Hospitalizations, ED Encounters
The real-world analysis measured the benefit of primary vaccination and of a booster and found the latter dependent upon local disease incidence and risk for severe disease.
Back Pain Gets Better but Also Recurs so Empower Patients Early with Tools
Recurrent back pain is common, so teaching patients how to stay strong and flexible—and also when to get help—is essential, says Vanderbilt physiatrist DJ Kennedy, MD.
First Opioid Use in Older Adults with Dementia Significantly Increased Mortality Risk
The highest risk of mortality among a Danish population with dementia occurred within 2 weeks of an opioid prescription but remained significant at 180 days.
Daily Dose: Flu Vaccination May Protect Against RSV in Children
Weekend Warriors Win; Self-Dx via Facebook; Eat This, Not That; +2 - the Five for Friday
Exercise pattern doesn't matter, just do it; self-diagnosis by social media; food will do when statins don't; plus portable T2D therapy and who really gets anticoagulation?