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GLP-1: Used Only as Needed

GLP-1: Used Only as Needed

GLP-1 works in an glucose-dependent manner on pancreasGLP-1 stimulates insulin release only when blood glucose is elevated. ...

The American Diabetes Association recommends diet, exercise, and metformin as “first-line” agents in the treatment of type 2 diabetes mellitus (T2DM). As a second line, there are many options—two of them injectable, ie, insulin and glucagon-like peptide-1 (GLP-1) receptor agonists. The GLP-1 agonists are not brand new, but primary care is still testing them out. Test yourself on the class with a short quiz.

1. Which of the following characterize of the hormonal perturbations that occur in T2DM?

A. Less insulin secretion from the pancreas

B. Increased glucagon secretion from the pancreas

C. Attenuated response to insulin in peripheral tissues (ie, liver and muscle cells)

D. A and C

E. All of the above

Please click here for answer, discussion, next question.


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