The most common manifestation of oropharyngeal
candidiasis (OPC) is pseudomembranous candidiasis, commonly
known as "thrush," which appears as a whitish yellow,
curdlike discharge on the mucosal surfaces. Other forms of
OPC include denture stomatitis, angular cheilitis, and glossitis.
Patients with denture stomatitis are usually asymptomatic, but
the tissue beneath the denture is typically red and hyperplastic.
Patients with angular cheilitis may complain of a burning sensation
at the margins of the lips. Candidiasis involving the
tongue can be exuberant and is usually associated with complaints
of a white tongue, taste alterations, and a burning sensation
of the tongue. The diagnosis of OPC can be established
by identifying typical fungal elements on potassium hydroxide
preparation or Gram stain of scraped material. Treatment options
include clotrimazole, fluconazole, itraconazole, and nystatin.
(J Respir Dis. 2008;29(3):128-135)