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Journal Of Respiratory Diseases

Journal Of Respiratory Diseases

de Jong YP, Uil SM, Grotjohan HP, et al, Isala Klinieken, Zwolle, and University Medical Center Gronigen, the Netherlands. Oral or IV prednisolone in the treatment of COPD exacerbations. A randomized, controlled, double- blind study. Chest. Dec 2007;132:1741-1747.

When untreated, inhalational anthrax typically results
in a rapidly fatal illness. Evidence suggests that both the
anthrax vaccine and prophylaxis with ciprofloxacin or doxycycline
are effective in preventing illness after inhalational anthrax
exposure. The current anthrax vaccine appears to have an
adverse-effect profile that is similar to that of other adult vaccines.
For patients with active infection, the CDC recommends
a multi-antibiotic regimen that should include doxycycline or
a fluoroquinolone and 2 additional antibiotics that have protein
or RNA synthesis inhibition, such as rifampin and clindamycin.
Monoclonal antibodies directed against anthrax toxins
may also play a role in treating active infection. (J Respir Dis.
2008;29(6):249-254)

A previously healthy 58-year-old man presented to the emergency department with a 4-week history of gradually progressive dyspnea, facial flushing, and night sweats. Three weeks before presentation, he received the diagnosis of acne rosacea from an outside physician and was given topical treatments, with no relief in symptoms. One week before presentation, he began to notice swelling of the face, neck, and right arm and dysphagia (initially with solids, then progressing to liquids).

• The evaluation of cough remains an important clinical problem for primary care physicians and pulmonologists alike. In the past 5 years, the American College of Chest Physicians,1 the British Thoracic Society,2 and the European Respiratory Society3 have published comprehensive guidelines to assist in standardizing the approach to cough evaluation. While determining the cause of cough can be vexing initially, prospective studies have shown that the cause can be established in more than 90% of patients.

Venous thromboembolism (VTE) continues to be a common and potentially life-threatening problem, with an estimated incidence of at least 1 in 1000 persons per year.1,2 VTE includes both deep venous thrombosis (DVT) and the resultant pulmonary embolism (PE). PE occurs in as many as 50% of patients with proximal DVT.3

Cryptococcus neoformans
most commonly infects persons
with an underlying T-cell
immunodeficiency. It has
been nicknamed the "sugarcoated
killer" because it can
cause a devastating disseminated
illness in immunosuppressed
patients. C neoformans
rarely causes primary
infection in an immunocompetent
patient. We present a
case of pulmonary cryptococcosis
that occurred in an otherwise
healthy man.

Microscopic colitis is a noninfectious
colitis that is characterized
by chronic nonbloody
diarrhea and macroscopically
normal colonic mucosa. Extraintestinal
manifestations
are rarely seen. In this report,
we describe a nonspecific interstitial
pneumonitis in a patient
with lymphocytic colitis.

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