A 47-year-old woman with a history of non-melanoma skin cancer presented for a total body skin check. During the examination, a 5 3-mm pigmented macule was noted on the anteromedial aspect of the right foreleg. Most important, the asymptomatic lesion had a small spot of eccentric darker pigmentation. The patient was unaware of the questionable growth. This type of eccentric pigmentation strongly suggests malignant melanoma. Since the lesion was so small, it was excised with 5-mm margins. Histology demonstrated malignant melanoma in situ.