Sweet Syndrome
November 01, 2007

A 66-year-old woman was hospitalized because of severe anemia secondary to myelodysplastic syndrome. She had had associated fatigue and throbbing pain in both legs for several days.

Pyoderma Gangrenosum on Both Legs of a 62-Year-Old Woman
November 01, 2007

Worsening painful ulcers on both legs prompted a 62-year-old woman to seek medical attention. She had a history of rheumatoid arthritis (RA), demonstrated by the markedly deformed interphalangeal joints in her thumbs (A), and scleroderma-polymyositis overlap syndrome.

Glucagonoma Syndrome
November 01, 2007

A 74-year-old woman presented with a refractory pruritic eruption. Four months earlier, she had sought evaluation of a thickened, slightly crusted 6 3 8-cm patch on her right ankle of 2 months' duration. Contact dermatitis with secondary impetigo from scratching was suspected, and a topical corticosteroid and an oral antibiotic were prescribed.

Asthma Drug Shows Promise in Pancreatic Cancer
December 19, 2006

HOUSTON -- Cromolyn, an old-line asthma and allergy drug, has shown a marked effect on the progress of pancreatic cancer - at least in mice.

Shedding Light on the Controversy Over Vitamin D
December 01, 2006

During a routine checkup, a middle-aged woman asks you whether she should stop wearing moisturizers and makeup that contain sunscreen. She has read that increased sunlight exposure enhances vitamin D production, which may prevent certain types of cancer. What would you tell her?

Oncology Q&A
May 01, 2006

Is prophylactic oophorectomy recommended for healthy postmenopausal women with a strong family history of cancer?

Multiple Lung Neoplasms
September 14, 2005

For the past 6 weeks, a 72-year-old woman with a history of ovarian cancer had had intensifying dyspnea. Initially, she thought her breathing problem was caused by progressive congestive heart failure.

Pancreatic Carcinoma: Painless Course but Deadly
May 01, 2003

A 74-year-old man had vague abdominal pain, jaundice, pruritus, gray stools, and dark urine. A painless, palpable mass in his right upper quadrant was found at examination.

Sister Mary Joseph Nodule
May 01, 2003

An 85-year-old man presented with intermittent abdominal pain of several years’ duration. Two years earlier, he underwent a laparoscopic cholecystectomy that was converted to an open procedure.

Ovarian Tumor in a 55-year-old Woman
November 01, 2002

For 2 years, a 55-year-old woman’s abdomen gradually enlarged; the pace of this growth had accelerated during the last 6 months. The patient, who had not seen a physician in 10 years, denied abdominal pain, nausea, vomiting, constipation, diarrhea, or any change in bowel habits. She had no shortness of breath or weakness. The patient reported no significant medical history, had no allergies, and took no medications.