Answer: D. Charlson Comorbidity Index (CCI). The CCI is a more general index that is not specific to COPD; it is the most commonly used index for predicting overall survival related to a wide range of comorbidities. The COTE was the first index developed to assess mortality risk in relation to comorbidities in COPD. The CODEx index is used in patients who have been hospitalized with COPD exacerbations to help predict death, hospital readmission, and a composite of these two 3-12 months after discharge. The COMCOLD index evaluates the impact of common COPD-related comorbidities on a range of patient-reported outcomes.2
4. COPD and asthma are mutually exclusive.
1. Smith MC, Wrobel JP. Epidemiology and clinical impact of major comorbidities in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2014;9:871-888.
2. Negewo NA, Gibson PG, McDonald VM. COPD and its comorbidities: Impact, measurement and mechanisms. Respirology. 2015;20:1160-1171.
3. Hillas G, Perlikos F, Tsiligianni I, Tzanakis N. Managing comorbidities in COPD. Int J Chron Obstruct Pulmon Dis. 2015;10:95-109.