Answer: B. Successfully treating HCV can cause regression of low-grade lymphomas. HCV is associated with increased risk for B-cell non-Hodgkin lymphoma. Eliminating HCV decreases the risk for this cancer but does not eliminate it. Accumulating evidence suggests that successfully treating HCV may lead to regression of low-grade lymphomas.2 Some evidence supports treating these patients with direct-acting antivirals (DAAs) without immediate chemotherapy, followed by close surveillance.2 Studies suggest that treatment for active HCV and chemotherapy for aggressive B-cell lymphomas may improve lymphoma response. Using DAAs may cause less toxicity than interferon-based regimens.2
5. Confirmation of HCV-related renal disease requires which of the following?
B. Microscopic hematuria
C. Decreased creatinine clearance
D. Renal biopsy