High sustained virologic response rates were seen among patients with decompensated cirrhosis in European compassionate care cohort.
Sustained virologic response was seen in 99% of subjects, reflecting rates seen in pre-registration studies. Adverse events were mild.
A modeling study compared health benefits and costs of all currently licensed treatments, both singly and in sequential therapy of up to 3 lines.
With new direct-acting antiviral agents, a rapid virological response was observed in a majority of patients.
SVR12 rates are high with sofosbuvir-based treatment regimens even when patients receive less than a full course of treatment.
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Q:My patient has an elevated hemoglobin concentration and hematocrit; however, the reticulocyte count, ferritin level, results of hemoglobin electrophoresis, and total iron-binding capacity are normal. What is the next step after common causes of an elevated hemoglobin concentration and hematocrit, such as chronic obstructive pulmonary disease, have been ruled out?
Our laboratory has begun reporting group G β-hemolytic streptococci in addition to group A on throat cultures.