Four trials of moderate-quality evidence found no significant improvement in pain control in acute gout with NSAIDs vs COX inhibitors. But there was evidence that patients stopped NSAIDs early because of adverse events.
Gout attacks really do occur more often at night, and here is proof. Theories abound as to why, but effective prophylactic treatments to reduce the risk of nocturnal exacerbations appear to be just what the doctor ordered.
A large population study shows that people with gout may have a reduced risk of dementia -– including Alzheimer’s disease. This is a significant finding and may support theories that uric acid has antioxidant properties and possible neuroprotective effects.