Therapies that target specific pathways or proteins in cancer cells are especially noted for dermatologic events, which affect up to 90% of treated patients.
Unexplained Hair Loss in a 4-Year-Old Boy
The diagnosis of trichotillomania seemed certain, despite lack of supporting history. It turned out to be about 50% wrong.
A Female Teen with Swollen Feet
A 10-month history of progressive swelling below the knee makes this 12-year-old's case an ideal stop on the medical mystery tour.
The Mysterious Case of the Boy who Barked
A 14-year-old with an odd facial rash has vocal outbursts at school, especially when teased and at home when stressed. What’s wrong? Dx?
A Rash That Didn't Make Sense
It looked very much like dermatomyositis, but there were no signs of muscle weakness. What would be in your differential diagnosis?
Hemiscrotal Bulge in an Otherwise Normal Neonate
A compressible groin swelling is the only abnormal feature after full-term gestation and unremarkable delivery. Your Dx?
Acne and a Hickey: What is Wrong with Vickie?
The 16-year-old is upset by a new outbreak of “acne” and the prom is in 2 weeks. But is it acne? And what’s that bruise?
Sore Throat and Widespread Rash in a Young Sailor
A young naval recruit presents with a cluster of symptoms that may sound familiar. Get more clues and a close look at the rash, here.
Acute Widespread Rash in a 9-month-old Boy
What is the cause of this erythematous rash that appeared suddenly and spread rapidly on the child's trunk and extremities?
A 13-year-old Girl with a Vesicular Rash on Palms
VIDEO: The child's hands are chronically dry but the skin has recently begun to crack; vesicular rash appeared after an ocean swim. Dx?
Progressive Rash and Arthralgias in a Teenage Male
PT Video: A short course of steroids was ineffective. He returns to ED c/o worsening joint and abdominal pain. Can you Dx?
Head-to-Toe Rash on a 17-year-old Boy
VIDEO: The non-pruritic rash began on his chest and spread rapidly over 3 days. Get a closer look; what's your diagnosis?
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