Annette is 61-years-old; she is treated for hypertension but today is concerned about her risk for heart attack because her father had a first MI at age 60. How would you proceed?
Michael Shapiro, MD
Although proton pump inhibitors (PPIs) are highly effective, clinical failure in patients with gastroesophageal reflux disease (GERD) is seen regularly--not only in GI clinics but also in primary care offices. In fact, the prevalence of failure with PPIs has increased in proportion to the expanding indications for their use.