Weekly Dose Podcast: New Obesity Data, Insulin Guidance, and Mental Health Screening

The latest episode of the Weekly Dose Podcast from Patient Care® Online delivers a concise roundup of five key clinical updates relevant to primary care. Below are this week’s key highlights.

Updated Insulin Prescribing Guidance Aims to Support Individualized Diabetes Care

The FDA issued updated prescribing information for inhaled mealtime insulin powder, including a revised starting-dose conversion table to assist clinicians transitioning adults from injected rapid-acting insulin. The changes aim to improve dosing accuracy and postprandial glucose control in routine practice.

Primary Care’s Expanding Role in Obesity and Cardiometabolic Risk

Obesity specialist insights emphasize the central role of primary care in early identification and management of obesity as a driver of cardiometabolic disease. Integrating lifestyle strategies, risk stratification, and thoughtful use of emerging therapies can help address long-term cardiovascular risk.

Dual GLP-1/GIP Agonist CT-388 Demonstrates Substantial Weight Loss

Phase 2 data for an investigational dual GLP-1/GIP agonist showed a 22.5% placebo-adjusted weight loss, pointing to a potential next generation of pharmacologic options for obesity management beyond current treatments.

Evidence-Based Communication Strategies for Vaccine Hesitancy

With vaccine hesitancy persisting as a clinical challenge, the episode summarizes strategies for empathetic and trust-preserving communication. Clinicians are encouraged to engage in patient-centered dialogue that addresses concerns without alienating hesitant individuals.

Depression Screening With Bipolar Disorder in Mind

The final segment highlights the importance of structured depression screening in primary care while keeping bipolar disorder in the differential. Careful assessment can help prevent misdiagnosis and inappropriate therapy, a critical consideration for patients presenting with depressive symptoms.

Listen to the full episode above for deeper clinical context and practical takeaways for primary care.