Sleep Disorders

This marks the second indication for tirzepatide in just more than a year, following its November 2023 approval for adults with obesity or overweight and weight-related medical problems.

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Review authors emphasized the need for a more comprehensive approach to dementia management.

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Findings from a recent review highlight the impact of common analgesic medications on sleep patterns in people with chronic pain.

ADA 2024. Adults with OSA and obesity receiving tirzepatide had improvements in sleep apnea severity and systolic blood pressure compared to placebo.

Details on tirzepatide for obesity-related obstructive sleep apnea, semaglutide for prevention of major kidney outcomes in patients with T2D and CKD, more.

Find details on optimizing diabetes care in primary care settings, benefits of GLP-1RAs for patients with HF and diabetes, and tirzepatide use for obesity-related OSA.

Tirzepatide reduced OSA symptoms and body weight in study participants with severe OSA and obesity, regardless of use of positive airway pressure therapy.

Women aged 40 to 65 years who had persistent insomnia and poor sleep duration were at a 75% greater risk for incident CVD over 2 decades of follow up.

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The effect of vagus nerve stimulation persons with narcolepsy revealed a specific, notable improvement in daytime sleepiness in a novel open-label study.

Use of dupilumab also eliminated the need for use of a rescue inhaler in more than one-third of treated patients and the number of inhalations needed for others.

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A recent study of patients with chronic low back pain sheds light on the association between sleep and opioid use on pain severity and interference.

Women with an evening vs morning chronotype were 54% more likely to have unhealthy lifestyles that in turn accounted for a significant increased risk for diabetes.

Obesity medicine specialist and internist Alina Elperin, MD, shares why screening for obstructive sleep apnea and metabolic disease in patients with obesity is crucial.

Cluster headache and migraine are described as "highly circadian at multiple levels," suggesting hypothalamus involvement and potential for new treatments, study authors say.

ACC 2023. A large study found increased risk for MI regardless of age and detected particularly heightened risk among women and persons with diabetes who have insomnia.

Sleep duration irregularity was associated with measures of subclinical atherosclerosis in a racially and ethnically diverse study of more than 2000 adults.

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A 2-sample Mendelian randomization analysis showed that sleep apnea and snoring increased the risk of HTN and CAD, and these associations may partly be driven by BMI.

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New findings suggest that the elevated risk of overdose with benzodiazepine use for sleep disorders is a critical safety consideration when treating young people.

Nocturnal HTN is a risk factor for cardiovascular disease and stroke. How do you diagnose and treat in your practice? Test your overnight BP IQ.