November 27th 2024
The proposal would expand antiobesity drug access for more than 7 million people with Medicare and Medicaid coverage.
November 26th 2024
The investigational weight loss drug showed substantial weight loss among people with obesity or overweight with or without T2D without plateaus.
November 22nd 2024
Your daily dose of the clinical news you may have missed.
November 21st 2024
Millions of US adults could benefit from semaglutide treatment for diabetes, obesity, and/or CV disease but insurance isn't guaranteed and the drug is costly.
November 20th 2024
The Future of GLP-1RAs in Obesity Treatment: Expert Perspective
With the recent surge in demand and supply shortages, Michael Crotty, MD, discusses the future of GLP-1RA use in the treatment of obesity.
How Primary Care Physicians Can Approach the Use of GLP-1 Receptor Agonists for Weight Loss
Michael Crotty, MD, provides practical guidance for on integrating GLP-1 receptor agonists into a comprehensive obesity treatment plan.
GLP-1RAs for Weight Management: Weighing Benefits vs Side Effects
Obesity medicine specialist Michael Crotty, MD, discusses the benefits of GLP-1 receptor agonist use in weight management and its impact on obesity-related comorbidities.
Expanding the Obesity Treatment Toolbox: The Promise of Dual-Action Medications
Michael Crotty, MD, an expert in obesity medicine, discusses GLP-1RAs in the context of weight loss, including the novel dual agonist survodutide.
GLP-1RAs Cut Early Colorectal Cancer Risk in Adults with T2D: Daily Dose
Death Rates from Obesity-Related Heart Disease Soared Nearly 200% Between 1990 and 2020, Researchers Report
AHA 2024. "...we did not anticipate this magnitude of increase in mortality," researchers said. They were also surprised by the population groups most affected.
8 Antiobesity Therapies to Watch Closely
Dual and triple incretin agonists continue to lead the new therapies in the antiobesity pipeline. Here is an at-a-glance update of their progress toward approval.
New Phase 3 Trials Investigate Survodutide as a Promising Treatment for Obesity
SYNCHRONIZE-1 and -2 will provide "robust evidence" on the safety, efficacy, and tolerability of survodutide in adults with obesity with or without T2D.
Semaglutide 2.4 mg Reduces Risk for Hospitalization for Any Cause in Adults with CVD, Obesity
ObesityWeek 2024. Semaglutide 2.4 mg reduces rates of composite CV outcomes in high-risk patients without diabetes and now is shown to reduce inpatient care and length of stay.
ObesityWeek 2024: Viking Therapeutics Presents New Positive Data from VK2735 Obesity Program
Results from the VENTURE phase 2 trial and a phase I oral formulation study found that VK2735, a dual GLP-1 and GIP receptor agonist, demonstrated promise in treating obesity.
Metabolic Bariatric Surgery Takes a Backseat as GLP-1RA Use Soars, According to New Research
Clinicians should continue to monitor trade-offs between pharmacologic and surgical management of obesity, researchers said.
GLP-1RAs Reduce the Risk of Early-Onset Colorectal Cancer in Adults with T2D
ACG 2024: New study results indicate GLP-1 RAs have a potentially protective role to play in combating EO-CRC, the incidence of which is notably rising worldwide.
Exclusive Physician Survey Results on GLP-1 Receptor Agonists: The Hype Is Real
Three-quarters of primary care survey respondents prescribe GLP-1 RAs for weight loss and half get questions daily about the drugs. See all the results.
Understanding the Obesity-Hypertension Connection: A Clinician Discussion
Caissa Troutman, MD, provides an overview of the connection between obesity and hypertension.
Pharmacotherapy Recommendations for Obesity Management from the AGA: A Guideline Topline
Antiobesity medications are the next step after lifestyle interventions prove inadequate; here are the American Gastroenterological Association recommendations, at-a-glance.
GLP-1RAs May Lower Risk of Suicidal Ideation for Youth with Obesity, New Data Suggest
In a study of adolescents with obesity, those in the GLP-1RA group had a 33% lower risk of experiencing suicidal ideation or attempts compared with matched controls.
Obesity Management Demands Much More than Medication
Obesity is a complex disease that requires a multispecialty approach to address the physical and also the mental and emotional components of the widespread disorder.
Novel Oral Antiobesity Drug Reduces Body Weight by up to 13%: Daily Dose
Novel Oral Antiobesity Drug Shown to Reduce Body Weight by up to 13% in First-In-Human Study
EASD 2024: Amycretin was also found to be safe and well tolerated in adults with obesity and without diabetes.
Mental Health Among Adolescents With Obesity: Daily Dose
Survodutide: Novel GCGR/GLP-1RA Shows Promise in Obesity, MASH Treatment
EASD 2024: New data shows survodutide may be beneficial for persons with obesity and MASH.
Novel GLP-1 RA for Obesity Shows Promise in Early Phase 1 Trial
Once-daily oral TERNS-601 was associated with a significant mean 5% weight reduction after 28 days and had a favorable tolerability profile.
Tirzepatide Reduces Risk for Progression from Prediabetes to T2D: Daily Dose
New Findings Underscore Importance of Mental Health Screening in Adolescents Receiving Obesity Treatment
In a study of adolescents with obesity, symptoms of depression and eating disorders decreased over the course of a 52-week intensive behavioral intervention.
Lilly Makes Tirzepatide Single-Dose Vials Available as Self-Pay Option at 50% Discount
Vials of tirzepatide 2.5 mg and 5 mg will be available with a prescription for the labeled drug through LillyDirect after completing a multistep verification process, the company said.
Obesity in the Time of COVID: Expert Insights on the Physical, Emotional Toll on Patients
Patients with obesity face both physical and emotional challenges during the COVID-19 pandemic. How can PCPs help?
Effectiveness of Anti-Obesity Drugs for CVD Prevention: A Clinician Discussion
Anila Chadha, MD, talks to Patient Care about how antiobesity medications can aid in reducing CVD risk in patients with obesity.
Tirzepatide Cuts Risk of Progression to T2D by 94% Over 3 Years in Adults with Obesity, Overweight
Results of the 3-year SURMOUNT-1 study reflect the longest trial to date of tirzepatide in adults with overweight/obesity and risk for developing T2D.
Cardiovascular Disease Prevention in Patients with Obesity: An Expert Perspective
Anila Chadha, MD, highlights key preventive strategies to reduce CVD risk in patients with obesity and how to tailor them to address individual patient needs.
Shifting Trends in GLP-1RA Prescriptions: Daily Dose