Similar reduction in risk was reported for both lobar and nonlobar intracranial hemorrhage with longer statin treatment associated with greater protection, according to Danish investigators.
Approved in 2020 as Nexletol, bempedoic acid as the first ATP citrate lyase inhibitor and oral non-statin therapy to meet the MACE-4 primary endpoint.
Being most physically active in the late morning had a 16% decreased risk of coronary artery disease and a 17% decreased risk of stroke compared to midday.
"Cardiac rehabilitation is for life," says the NYU Langone Rusk Rehabilitation medical director of cardiac/pulmonary rehab, and he advocates empathy and compassionate understanding.
Study participants who had HZ were at 30% greater sustained risk of stroke and CHD vs those who had not had HZ in this large multicohort prospective study.
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Study authors saw a positive dose-response relationship driven by hemorrhagic stroke in young adults who were moderate-to-heavy drinkers in their 20s and 30s.
Apixaban was associated with up to a 28% lower risk of GI bleeding vs the 3 other direct oral anticoagulants in the first large-scale comparative analysis.
Black patients were also at significantly increased risk of stroke, bleeding, and mortality vs White patients 1 year following discharge.
In the absence of randomized controlled head-to-head trials comparing the 2 anticoagulants, study authors say clinicians should consider their findings when choosing treatment.