September 12th 2023
Your daily dose of clinical news you may have missed.
September 1st 2023
Atrial fibrillation prevalence is rising across socioeconomic strata globally, the new analysis finds, with effects of BMI, ETOH, and sedentary behavior shifting as key drivers.
August 28th 2023
Oldest and most frail elderly were at more than 60% greater risk of bleeding when switched from a VKA than those who remained on the traditional agent.
August 8th 2023
The reduction in risk of CV events, the first to be shown by an antiobesity drug, was higher than expected and could help alter perceptions of the agents as "lifestyle drugs."
July 27th 2023
A new analysis of the ASPREE trial of aspirin for primary prevention in older adults finds a poor risk-benefit ratio for prevention of stroke.
10 Questions on Adult Blood Pressure Targets Based on AAFP Guidelines
The 2022 AAFP Clinical Practice Guideline on hypertension treatment in adults is the subject matter for this 10-question topline quiz that is also a good source of review.
The Worst States for Health Care in the US: 2023
Get a quick look at the US worst states for health care ranked using a composite score that included measures of cost, access, and outcomes.
Daily Dose: Care for Acute Stroke in Women Less Urgent
A daily dose of clinical news you may have missed.
Concentrated and Distributed Physical Activity Similarly Lower Risk for CV Events
Regardless of the pattern of physical activity, it may reduce risk across a spectrum of cardiovascular diseases, say study authors. So, just do it!
Women with Acute Ischemic Stroke Routed Less Often to Optimal Acute Care
Disparities in emergency routing persisted despite women being acutely sicker than men and living the same distance from a comprehensive stroke center, in a Houston, Tx study.
Daily Dose: Association of Population Wellbeing with Cardiovascular Outcomes
Higher Community Wellbeing Linked to Reduced CVD Mortality in Study of More than 3000 US Counties
Wellbeing is considered a measurable and modifiable community attribute that study authors show is correlated with CV outcomes.
Daily Dose: Cardiovascular Safety of Testosterone-Replacement Therapy in Men with Hypogonadism
Healthy Lifestyle Linked to Primary CVD Prevention in Postmenopausal Women with Normal BMI
Higher scores on a healthy lifestyle index were associated with significantly reduced risk of incident CVD among women aged 50-79 years with BMI between 18.5 and 25.0.
Testosterone Replacement Does Not Increase Risk for CV Events in Men with Hypogonadism, New Study Finds
ENDO 2023. In older men with hypogonadism and CVD, there was no difference in incident CVD between those taking testosterone and those taking placebo.
Daily Dose: Bempedoic Acid Found Comparable to Statins for Lowering LDL-C
Bempedoic Acid Found Comparable to Statins for Lowering LDL-C, Reducing Major CV Event Risk
ENDO 2023: Treatment with bempedoic acid was found comparable to statin therapy in an analysis of the CLEAR Outcomes trial based on CTT Collaboration methodology.
Milvexian, FXIa Inhibitor, Wins US FDA Fast Track Designation for 3 Indications in Phase 3 Trial Program
Proposed indications for the investigational factor XIa inhibitor are: stroke prevention after acute ischemic stroke or high-risk transient ischemic attack; recent acute coronary syndrome; and atrial fibrillation.
Asundexian Granted FDA Fast Track Designation for Stroke Prevention in Patients with AF
Bayer's investigational FXIa inhibitor is currently being studied in a large-scale phase 3 development program expected to enroll more than 27 000 participants.
Daily Dose: Migraine without Aura Raises Stroke Risk for Women on Combined Hormonal Contraceptives
Daily Dose: Global Deaths from Ischemic Stroke May Reach 5 Million by 2030
Migraine without Aura May Increase Stroke Risk for Women Taking Combined Hormonal Contraceptives
The findings contradict published clinical guidelines that warn against use of estrogen-containing birth control by women who have migraine with aura.
Statin Therapy May be Protective Against Stroke in People with Atrial Fibrillation: New Study
Statin therapy initiated within 1 year of diagnosis of atrial fibrillation reduced the risk of ischemic stroke or systemic embolism by nearly 20%.
Global Deaths from Ischemic Stroke May Reach 5 Million by 2030, According to New Study
Findings also showed that between 1990 and 2019, the global number of ischemic stroke deaths rose from 2 million to 3 million.
Daily Dose: Physician and Patient Perspectives on Oral Anticoagulation for AF
"Disconnect" on Oral Anticoagulation Observed Between Patients with AF and their Physicians
More than two-thirds of patients not receiving OAC were open to beginning treatment but many of their physicians were not, according to a study of PINNACLE Registry participants.
Daily Dose: Statin Effects in AF-related Stroke
New Data Support Use of Statins in Patients with New-onset Atrial Fibrillation to Prevent Stroke, Transient Ischemic Attack
EHRA 2023: Patients with AF who started statins within a year of diagnosis had reduced risks of stroke and TIA compared with those who did not start statins.
FDA Proposed Rule Change Expands Use of Salt Substitutes to Lower NaCl Intake, Reduce Chronic Disease
The rule change would provide flexibility in standards that govern specific ingredients used in food production, permitting replacement of regular sodium with less toxic substitutes.
Risk of Stroke May Diminish with Age in Persons with Diabetes and Hypertension: New Findings
The magnitude of the association with age did not change, however, for other stroke risk factors, including smoking, atrial fibrillation, and LVH, investigators report.
Black and Hispanic Americans Less Likely to Receive Treatment for Post-Stroke Complications, Large Analysis Finds
Researchers found that Black and Hispanic Americans were less likely to be treated for certain poststroke complications, such as mood and spasticity, compared to White adults.
Daily Dose: Preeclampsia and Risk of Premature Ischaemic Cardiovascular Disease
Preeclampsia Linked to Significantly Increased Risk for AMI, Stroke 20 Years After Delivery
A study of more than 1.5 million women with a history of preeclampsia found up to a 4-fold higher risk of MI and 3-fold increased risk of stroke within 10 years of delivery.
Concomitant Gestational Diabetes and Hypertensive Disorder Increase Long-term Postpartum CVD Risk
Having both conditions while pregnant in the current study conferred more than double the risk of future CVD vs having either condition alone.
Statin Treatment and Duration Associated with Reduced Risk of Hemorrhagic Stroke
Similar reduction in risk was reported for both lobar and nonlobar intracranial hemorrhage with longer statin treatment associated with greater protection, according to Danish investigators.
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