Neurology

The CLEAR Outcomes PI explains the patient selection approach for bempedoic acid, now approved to reduce risk of CV events in addition to lowering LDL-C.

Labeling for triptan medications warns of potential for ischemic events but is the concern theoretical or real? A new study tests the association.

Atogepant was associated with fewer monthly migraine days, fewer acute medication use days, and greater QoL compared with rimegepant after 12 weeks.

The phase 4 APPRAISE trial found greater efficacy with erenumab after failure with 1 or 2 other preventives vs ongoing treatment with the nonspecific oral agents.

The sBLA for once-monthly maintenance IV dosing of lecanemab is complete but a rolling application for a weekly subQ option has been set back, said Eisai.

Your daily dose of the clinical news you may have missed.

Your daily dose of the clinical news you may have missed.

Even activity levels considered "insufficient" by guideline standards were found protective against stroke in this new systematic review and meta-analysis.

A man in his eighties presents to the ED after 1 week of persistent bilateral leg weakness and dysgeusia that has not worsened. What's your Dx?

Your daily dose of the clinical news you may have missed.

The surprise request for review of the phase 3 TRAILBLAZER-ALZ-2 clinical trial findings will delay the original PDUFA timing beyond first quarter 2024.

Your daily dose of the clinical news you may have missed.

Your daily dose of the clinical news you may have missed.

Women with migraine and persistent VMS faced double the risk of CVD and triple the risk of stroke, reported researchers.

Which city has the highest depression rate? Or the fewest work hours? Find the answers and more insights from a nationwide analysis, here.

The accuracy of the test in detecting Aβ and tau pathology underscores its potential to become an accessible and cost effective tool for Alzheimer diagnosis.

Atogepant once daily reduced mean monthly headache days in adults for whom up to 4 classes of oral migraine preventives were ineffective.

At 3 months following ischemic stroke, lower mean oxygen saturation but not apnea-hypopnea index was associated with functional deficits, according to a French research team.

Your daily dose of the clinical news you may have missed.

Your daily dose of the clinical news you may have missed.

Comprehensive management of T2D in primary care settings reduced risk of all-cause dementia by 28%, with lower HbA1c linked to lower, but still elevated risk.

Women aged 40 to 65 years who had persistent insomnia and poor sleep duration were at a 75% greater risk for incident CVD over 2 decades of follow up.

Anticoagulation and antiplatelet therapy appeared equally effective in reducing risk of recurrent stroke following cryptogenic stroke in persons with evidence of atrial cardiopathy.

Fever and confusion bring the young man in his twenties to the ED; roommates relate he's been weak and flu-like for 5 days. What's your diagnosis?

Your daily dose of the clinical news you may have missed.

Your daily dose of the clinical news you may have missed.

In apixaban-treated participants, risk of stroke or systemic embolism was reduced by 37%; the risk of disability or fatal stroke declined by 49%, but with noted bleeding risk.

The 3-fold greater risk of subsequent stroke was observed in the Black Women's Health Study's youngest cohort, aged 24-34, investigators reported.

Heart disease has been the primary cause of death in the US for the last century, and yet 51% of adults do not recognize the fact.

Which medications are most effective for acute migraine management? A recent study assessed which ones appeared to work best based on reported patient experience.