Study Sheds Light on Wheat Sensitivity as an Emerging Clinical Entity
February 11, 2013

Results suggest that wheat sensitivity is a true clinical entity worthy of further study, and that it is a heterogeneous condition with at least 2 distinct subtypes. How this will translate into clinical practice will be an evolving research area, but clinicians should not expect gluten avoidance to disappear as yet another food fad.

Go For The Glory Quiz: Itchy Rash; Helminthiasis; Penile Nodule; Alopecia; Inflammatory Disease
January 04, 2013

Test your skills in this 5-question quiz: Go For The Glory Quiz: Itchy Rash; Helminthiasis; Penile Nodule; Alopecia; Inflammatory Disease

Celiac Disease Updated: Diagnostic Challenge and Gluten Sensitivity
October 23, 2012

Here: an update on the challenges of detection, diagnosis, and management of celiac disease and non–celiac disease and the importance of gluten sensitivity.

A Case of Depression
October 09, 2012

October 11th is National Depression Screening Day. But how do you screen, diagnose, and treat effectively given the time constraints of busy office practice?

Helminthiasis Presenting as Microcytic Anemia
September 05, 2012

Intestinal helminthes represent one of the most prevalent types of human parasitic disease and remain a major health problem in developing countries.

An Elderly Woman With IgA Lambda Multiple Myeloma and Kidney Disease
April 05, 2012

A 92-year-old woman presented with a 6-month history of progressively worsening fatigue, weight loss, generalized bone pain, and dyspnea on exertion. A skeletal survey found lytic lesions in the pelvis, sacrum, and calvarium (shown here).

A Young Man With Thousands of Colorectal Polyps: Anomalous and Benign? Or, Something Else?
April 02, 2012

Diagnostic colonoscopy revealed innumerable polyps carpeting the mucosa from the rectum to the cecum. Endoscopic findings and family history were most consistent with familial adenomatous polyposis.

What Cause of Persistent Diarrhea and Weight Loss?
March 21, 2012

A 28-year-old woman presents with a 4-month history of diarrhea and a 15-lb weight loss. She reports starting “another new diet” a few months ago but was in good health until these symptoms began. There is no family history of GI disease and no sick contacts. She denies recent travel.

A Middle-Aged Man With Painful Dysesthesias in the Lower Limbs
March 10, 2012

Diabetic peripheral neuropathy may develop in patients who have normal or impaired fasting blood glucose or impaired glucose tolerance, precursors to frank diabetes.

Myalgias in a 55-Year-Old Man, After a Camping Trip
March 09, 2012

A 58-year-old man presents with myalgias of approximately 1 week’s duration. He had been recently treated for sinusitis and symptoms resolved. His only medications were hydrochlorothiazide for hypertension and simvastatin for hyperlipidemia. He and his wife had gone camping 1 month before this visit.