February 11th 2015
Oral etidronate, IV pamidronate, and then zoledronate caused bone markers to normalize in this 80-year-old woman-temporarily. What’s going on? Answer this and questions on 3 other topics in this week’s quiz.
December 18th 2014
October 30th 2014
Orbital Pseudotumor Disguised as Orbital Cellulitis and Sinusitis
May 10th 2012A 58-year-old man with a past medical history of chronic sinus disease and hypothyroidism presented with left periorbital pain and erythema that worsened despite outpatient treatment with topical antibiotics. An outpatient CT scan showed pansinusitis and orbital stranding. The diagnosis was orbital cellulitis and sinusitis.
The Death of Wang Bei: Cosmetic Surgery as a Moral Choice
December 23rd 2010In my customized Google news, I have a category for cosmetic surgery. Most items that turn up are self-serving PR announcements, but recently there was lengthy coverage of the death during cosmetic surgery of aspiring Chinese pop star Wang Bei.
Unusually Severe Pharyngitis in a 19-Year-Old Woman
September 8th 2010A previously healthy 19-year-old woman presents with a sore throat that has become progressively more painful over the course of 1 week. She also has left-sided neck swelling, light-headedness, and intermittent headaches. She denies recent sexual activity.
Allergic Rhinitis: Update on Your Therapeutic Choices
March 31st 2010Many pharmacological options exist for allergic rhinitis. Intranasal corticosteroids are the most effective medication class for patients with moderate to severe symptoms; those with milder intermittent symptoms can be treated with a second-generation oral or intranasal antihistamine.
Adolescent Who Holds Her Hand to Her Face
March 30th 2010A 14-year-old girl is seen because of long-standing nasal itch, intermittent nasal congestion, and clear nasal discharge. Allergies to house dust mites and to cats shown on prior skin testing. Often has marked eye swelling when exposed to cats. Receives antihistamines when in flare-up and prior to cat exposure. The consumption of dairy products exacerbates all of the above.
Managing Allergic Rhinitis: The Role of Pharmacotherapy
November 10th 2009While avoidance measures are a key component of the treatment of allergic rhinitis, pharmacological therapies are often needed to adequately control symptoms. Intranasal corticosteroids are highly effective and are particularly useful in patients with moderate to severe disease.
Allergic Rhinitis: Update on Diagnosis
October 2nd 2009Allergic rhinitis is highly prevalent; about 20% of adults in the United States and 25% of children worldwide are affected. It is a major societal expense, with direct costs, attributable to physician visits and medications, of up to $5 billion per year, and indirect costs, mainly stemming from lost productivity, of up to $9.7 billion per year. In the United States, allergic rhinitis results in 3.5 million lost workdays and 2 million lost schooldays each year.
Woman With Fever, Hoarseness, and a Half-Swollen Face
July 1st 2008A 55-year-old woman seen because of new lump under right side of her jaw; present for 24 hours. Associated neck discomfort causing dysphagia, and also a raspy turn to the voice; both much worse in last 12 hours. No dyspnea. No sore throat.
Confirming the diagnosis of invasive fungal sinusitis
July 1st 2007Acute invasive fungal rhinosinus- itis occurs predominantly in immunocompromised patients, such as those with neutropenia and transplant recipients. The diagnosis requires biopsy, but permanent section can be time-consuming and result in a delay in treatment. Ghadiali and colleagues conducted a study to evaluate the accuracy of frozen-section biopsy in this setting.
A possible link between reflux and otitis media with effusion
March 1st 2007In addition to causing classic symptoms such as heartburn, gastroesophageal reflux (GER) is thought to cause a number of non-GI symptoms, such as cough and sore throat. Animal studies also suggest that GER may cause eustachian tube dysfunction. Now, a study from Japan indicates that there may be a link between GER and otitis media with effusion (OME) in adults.
Managing chronic sinusitis: Is 3 weeks of antibiotics enough?
February 1st 2007In the treatment of chronic rhinosinusitis, antibiotics are often given for 3 to 6 weeks, but the optimal regimen has not been established. Dubin and coworkers conducted a study to assess the effectiveness of a 3-week course. They found that for some patients, significant radiographic improvement occurs when antibiotics are given for more than 3 weeks.