A Diabetes Prevention Program Quiz: By the Numbers

Grace Halsey

The landmark Diabetes Prevention Program (DPP) trial and follow-up studies proved that risk of T2D can be reduced in patients at high risk for the disease. Do you know by how much?

The Diabetes Prevention Program (DPP [1996-2001]) was a randomized trial (N=3234) to compare an intensive lifestyle intervention or masked metformin vs placebo in a diverse cohort selected to be at very high risk of developing type 2 diabetes (T2D). Approximately 88% (2766) of the surviving DPP cohort were followed up in the DPP Outcomes Study (DPPOS, Sept 1, 2002, to Jan 2, 2014) and analyzed on the basis of their original DPP assignment. A third follow-up study at 15 years after randomization assessed the long-term effects of the interventions as well as their impact on development of microvascular complications.

Find out what you recall about the success of the DPP interventions with a short quiz on the numbers, ie, the percentage reduction in incidence of T2D in the treatment groups vs placebo over time.