A small punch biopsy showed basal cell carcinoma with focal hypermelanosis. The underlying erythema and punctuate superficial dark black pigmentation strongly suggested a dysplastic nevus or even a melanoma.
A 57-year-old man discovered a relatively small (1 cm), pigmented nodule of uncertain duration on his left arm during a cutaneous self-examination. The patient had a previous skin cancer.
Key point: The lesion displays an underlying erythema as well as punctuate superficial dark black pigmentation. While this strongly suggests a dysplastic nevus or even a melanoma, pigmented basal cell carcinoma can appear in this manner. A small punch biopsy disclosed basal cell carcinoma with focal hypermelanosis.
Treatment: The lesion was modestly sized and located on a low-risk skin region. Simple excision (with 5-mm borders) and primary closure was performed.
Note: The different diagnostic possibilities can be precise clinical mimics. Biopsy whenever doubt exists regarding the exact diagnosis.
Biden Administration Announces First 10 Prescription Drugs Slated for Price Negotiations
August 29th 2023The first 10 drugs identified for negotiations under the Inflation Reduction Act include several well advertised agents indicated to treat diabetes, heart failure, and other chronic diseases.