Dietary Factors in FGID: FODMAPS, Food Sensitivities, Vitamin D
3 Studies At-a-Glance based on presentations at Digestive Disease Week 2018, June 2-5, 2018 Washington, DC
Efficacy of the association between vitamin D and low FODMAPs diet for the treatment of irritable bowel syndrome
RCT of Low FODMAP Diet& Vit D Supplementation in IBS. Vitamin D deficiency and elevated dietary FODMAPs are both implicated in pathogenesis of IBS; study looked at impact on symptoms of implementing either low FODMAP diet or increasing vit D or combining both.
Significantly Improved IBS Symptoms with low FODMAP Diet + Vit D. Conclusions: Data seem to show an improvement in IBS symptoms clearly more evident in patients treated with the low FODMAPs diet and vitamin D compared with patients treated only with vitamin D and only with low FODMAPs diet.
Differences between fructose and lactose metabolism by microbiome during breath testing in patients with functional gastrointestinal disorders
Does Metabolism of Individual FODMAPs Vary? Study looked at patients with FGID who had fructose and/or lactose intolerance or malabsorption and compared symptoms after ingestion.
Lactose Intolerance: Delayed Symptoms with Longer Duration. Conclusions: Differential effects of individual sugars in FGID are likely to be of clinical consequence and need to be examined further.
Cytokine profile and IgE-mediated serological food hypersensitivity in patients with irritable bowel syndrome with diarrhea
Is There a Difference Between IBS-D with/without Food Allergy? Study evaluated IgE-mediated response to food allergens, serum cytokin levels, GI symptoms
Lower Inflammatory Profile in IBS-D with Food Allergies. Conclusions: Serologic test regarding IgE-mediated food allergy can detect a certain cluster of IBS-D
The slides above offer top-line results of new research presented at Digestive Disease Week 2018 -- specifically in the area of dietary factors that have an impact on functional gastrointestinal disorders. The 3 studies reviewed shed light on: The impact of vitamin D supplementation and low-FODMAP diet as treatment for irritable bowel syndromeThe difference in effects on FGID between fructose and lactose and implications for treatment The impact of food allergy on IBS-D and the future role for serologic testing in patient identificaton Â
