GERD Trends Shift and PPI Safety is a Question

June 6, 2018
Veronica Hackethal, MD
Veronica Hackethal, MD

News from DDW 2018: GERD is appearing in younger patients; PPI first use linked to many adverse events; and, new test for bile salts in saliva.

References Perez N, Shao JZ, Mittleman R, et al. Presence of Bile Acids Detected in Human Saliva using a Novel Sensitive Bioanalytical Method: A Comparative Study in Patients with Persistent or Controlled Gerd Symptoms and Healthy Subjects. Gastroenterology. 2018;154:S-484Elchert JA, Mansoor E, Saleh MA, Cooper GS. Epidemiology of First Time Proton Pump Inhibitor Users in the United States Between 2012 to 2017: A Population Based National Study. Gastroenterology. 2018; 154:S-232.Yamasaki T, Hemond C, Fass, R.  The Changing Epidemiology of Gastroesophageal Reflux Disease (GERD)- are We Seeing Younger Patients? Gastroenterology. 2018;154: S-233.