HANDBOOK OF DRUG INTERACTIONS: A CLINICAL AND FORENSIC GUIDE

December 31, 2006

Drug interactions and adverse drug reactions result in thehospitalization (or extended hospitalization) of more than100,000 Americans each year. Here an international teamof experts from such fields as pharmacology, toxicology, medicine,and nutrition discuss drug-drug interactions as wellas interactions that occur between drugs and certain foods,alcohol, nicotine, or performance-enhancing agents. Amongthe drug classes covered are benzodiazepines, anticonvulsants,opioids and opiates, monoamine oxidase inhibitors,tricyclic antidepressants, selective serotonin reuptake inhibitors,antipsychotic agents, cardiovascular drugs, antimicrobials,HIV/AIDS medications, and NSAIDs. The authorsreview the pharmacology, pharmacodynamics, pharmacokinetics,chemistry, and metabolism of each class. Also includedis an overview of the theories of liability used in recentdrug interaction litigation and a discussion of the role ofpsychotropic medications in criminal defenses. A detailedindex is provided.

Drug interactions and adverse drug reactions result in thehospitalization (or extended hospitalization) of more than100,000 Americans each year. Here an international teamof experts from such fields as pharmacology, toxicology, medicine,and nutrition discuss drug-drug interactions as wellas interactions that occur between drugs and certain foods,alcohol, nicotine, or performance-enhancing agents. Amongthe drug classes covered are benzodiazepines, anticonvulsants,opioids and opiates, monoamine oxidase inhibitors,tricyclic antidepressants, selective serotonin reuptake inhibitors,antipsychotic agents, cardiovascular drugs, antimicrobials,HIV/AIDS medications, and NSAIDs. The authorsreview the pharmacology, pharmacodynamics, pharmacokinetics,chemistry, and metabolism of each class. Also includedis an overview of the theories of liability used in recentdrug interaction litigation and a discussion of the role ofpsychotropic medications in criminal defenses. A detailedindex is provided.