Lower GI Distress in an HIV-Positive Young Man

A classic sign helps determine the diagnosis. Do you recognize it?

A 28-year-old HIV-positive man presents with several days of crampy abdominal pain and bloody diarrhea. He undergoes a colonoscopy, which demonstrates inflammation characterized by several large ulcers, erythema, and edema in the distal colon. Biopsy specimens reveal cells with large intracytoplasmic inclusions.

Which of the following would be the recommended treatment?

A. Ganciclovir
B. Prednisone
C. Acyclovir
D. Ciprofloxacin
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