“Stippled” pigment is highly typical of a pigmented basal cell carcinoma. Diagnostic contenders include atypical seborrheic keratosis and superficial spreading melanoma.
A 69-year-old homosexual man complained about an asymptomatic “dark spot” on his cheek. The lesion had been present at least 6 months. His medical history included rare actinic keratoses.
Key points: Physical examination disclosed a solitary, nearly flat patch, below and lateral to the right eye. The abnormal-appearing area was characterized by small areas of intense pigment. This is often referred to as “stippled” pigment and is very typical of a pigmented basal cell carcinoma. However, a biopsy was done to confirm this diagnosis and to rule out an atypical seborrheic keratosis or a superficial spreading melanoma.
Treatment: Due to the small size and the patient’s lack of cosmetic concerns, the lesion was vigorously subjected to 2 applications of curettage followed by electrodesiccation.
Note: This type of lesion may occur at any anatomical site, and biopsy confirmation is required.
Lebrikizumab Demonstrates Efficacy, Safety in Patients With Skin of Color With AD
June 11th 2025RAD 2025. Lebrikizumab improved skin clearance, itch, and pigmentation in patients with skin of color and atopic dermatitis, with strong safety data through 24 weeks, according to late-breaking data.