A Severe Pruritic Rash

What is the cause of this severe rash in a 60-year-old man with HIV?

A 60-year-old man with a history of HIV is seen in the ED for a severe skin eruption. He recently began a course of oral vancomycin for Clostridium difficile colitis. His other medications are nevirapine and abacavir/lamivudine which he re-started about 1 month ago after going off them temporarily. The only other symptom is the ongoing diarrhea which has slowed since starting the vancomycin.


What is the most likely diagnosis?

A. Eczema
B. Psoriasis
C. Drug reaction
D. Lymphoma/other malignancy
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