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What Treatment for Functional Chest Pain?

Poll

A 28-year-old woman is evaluated for chest pain, which is considered to be esophageal in nature. Her workup has included a normal upper endoscopy, a normal barium swallow, and a normal 24-hour pH/impedance study. She has tried a twice-daily PPI for several weeks without improvement in her symptoms.

Which of the following treatments would be recommended next?

A. Venlafaxine
B. Ranitidine
C. Baclofen
D. Metoclopromide
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