This 10-month-old boy presents with a red, macular, spreading rash that developed 5 days after he started taking amoxicillin for otitis media.

A. Erythema infectiosum (fifth disease; parvovirus B19)

Answer: A: Erythema infectiousum (fifth disease; parvovirus B19)

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A macular rash has been spreading for 5 days after the cheerful child started amoxicillin therapy.  What’s the most likely cause?