10-Month-Old With Macular Spreading Rash

A macular rash has been spreading for 5 days after the cheerful child started amoxicillin therapy. What’s the most likely cause?

This 10-month-old boy presents with a red, macular, spreading rash that developed 5 days after he started taking amoxicillin for otitis media.


What’s the most likely cause?

A. Erythema infectiosum (fifth disease; parvovirus B19)
B. Urticaria (hives)
C. Contact dermatitis
D. Viral exanthem
E. Drug rash
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