Allergic to Ester?

September 1, 2005

Some patients are allergic to ester-type anesthetics, such as procaine.

Some patients are allergic to ester-type anesthetics, such as procaine. In addition to substituting an amide-type anesthetic (such as lidocaine) in such patients, avoid using a multi-dose vial of any anesthetic; these all contain a paraben preservative that is clinically similar to ester-type local anesthetics. Single-dose vials do not contain preservatives.

- Bruce Becker, MD
   Bloomsburg, Pa

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