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Are Age-Appropriate Flu Vaccines Interchangeable?


A child receives a trivalent inactivated flu shot for his first ever flu vaccine. For his second dose, you only have on hand the quadrivalent live attenuated nasal vaccine. Is this a problem?

A healthy 26-month-old child is in your office. He received a 0.25 cc dose of a trivalent inactivated shot (Fluzone) 6 weeks ago as his first ever flu vaccine.


Which of the following should he receive today?

A. 0.25 cc of the trivalent shot (Fluzone)
B. A full dose of quadrivalent live attenuated nasal vaccine (FluMist)
C. 0.25 cc of a quadrivalent shot (Fluzone)
D. Any of the above
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