Physical activity was associated with up to 22% lower mortality and 19% lower stroke risk in adults with and without atrial fibrillation in a large Norwegian cohort study.
News|Slideshows|December 4, 2014
Five Top Papers From 2014 That Will Impact Your Practice
Author(s)Gregory W. Rutecki, MD
New drugs that treat stubborn illness seen often in primary care lead this group of Top 5 Papers for 2014. Type 2 diabetes, cryptogenic stroke, and hep-C are key targets.
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The best publications in a given year may be chosen because they are cited frequently, possibly because they warrant erudite editorials or because they are the most scientifically respected manuscripts. The road I’ve taken, however, is to select papers with results and/or conclusions that affect primary care practice-right now and for the immediate future.The references encompass situations and diseases that have frequently challenged me and are seen frequently in primary care: - Hepatitis C - Type 2 diabetes - Insomnia - Stroke - AnticoagulationÂ
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A team-based blood pressure intervention delivered through primary care reduced dementia risk by 15% over 7 years.
Tirzepatide gained an FDA cardiovascular indication after SURPASS-CVOT showed noninferiority to dulaglutide in high-risk adults.
Stroke incidence in adults aged 20–54 nearly doubled from 1993–1994 to 2020, driven largely by ischemic stroke, while 30-day fatality declined, according to new research.
The FDA has approved insulin efsitora alfa-gobe (Onswik) for adults with type 2 diabetes.
New research links type 2 diabetes and genetic risk to MASLD cirrhosis before 50, warning age-based fibrosis scores can miss severe disease.
FDA updates sotatercept-csrk label with HYPERION data, showing earlier use cuts PAH clinical worsening risk 76% alongside background therapy.
Finerenone wins FDA clearance for type 1 diabetes–related CKD, lowering albuminuria in FINE-ONE and opening a long-awaited treatment path.
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