Closing Thoughts on Treating Anaphylaxis with Epinephrine Nasal Spray
May 21st 2025A panelist discusses how education about anaphylaxis recognition, early epinephrine administration, and addressing barriers like device portability remains crucial, with intranasal epinephrine potentially solving many existing challenges in anaphylaxis management.
Real-World Case Examples: The Impact of Epinephrine Nasal Spray
May 21st 2025A panelist discusses how real-world cases demonstrate both the effectiveness of epinephrine when properly administered and the importance of ensuring patients actually carry their medication, through the stories of a college student with cashew allergy and a child undergoing a peanut challenge.
Clinical Perspectives on Real-World Utility and Impact of Epinephrine Nasal Spray
May 21st 2025A panelist discusses how Neffy offers significant advantages over traditional autoinjectors including longer shelf life (24-30 months), better temperature tolerance, and needle-free administration that addresses several unmet needs in anaphylaxis management.
Oral Food Challenge (OFC) Study with Epinephrine Nasal Spray
May 21st 2025A panelist discusses how the current anaphylaxis grading system classifies reactions from zero (no reaction) to four (death), with grade two representing moderate but significantly uncomfortable symptoms affecting multiple body systems.
Addressing Barriers to Epinephrine Use: From Reluctance to Readiness
May 21st 2025A panelist discusses how patient uncertainty about when to administer epinephrine and reluctance to use autoinjectors are major barriers to timely treatment, with over 40% not filling their prescriptions and 55-60% not consistently carrying their devices.
Why Epinephrine Is the Gold Standard in Treating Anaphylaxis
May 21st 2025A panelist discusses how epinephrine is definitively the first-line treatment for anaphylaxis regardless of severity, emphasizing that delayed administration is associated with poor outcomes including abnormal vital signs and increased risk of hospitalization.
Newer Nonsteroidal Topical Treatments for Atopic Dermatitis: JAK Inhibitors and AhR Agonists
May 14th 2025A panelist discusses how the ADORING trial for tapinarof demonstrated good efficacy and safety, but emphasizes that treatment choices for atopic dermatitis depend on patient needs, preferences, and the specific characteristics of their condition, with factors like speed of action, safety, and adherence playing key roles in decision-making.
Exploring Newer Nonsteroidal Topical Treatments for Atopic Dermatitis: PDE4 Inhibitors
May 14th 2025A panelist discusses how the real-world use of crisaborole, roflumilast, and ruxolitinib for atopic dermatitis reveals differing tolerability and efficacy, with roflumilast standing out for its superior results and ease of use while ruxolitinib is limited by safety concerns for larger areas of the body.
Risks and Adverse Effects of Long-Term Topical Corticosteroid Use
May 14th 2025The speaker discusses the challenges of treating patients with topical steroid withdrawal, emphasizing the need for careful steroid reintroduction and responsible use while also exploring newer nonsteroidal treatments for atopic dermatitis and the barriers to access due to high costs and limited comparative effectiveness data.