Assessing the cause of symptoms in a patient with thyroid cancer
February 1st 2007A 75-year-old woman had undergone a total thyroidectomy, with histologic evidence of poorly differentiated follicular thyroid cancer. She subsequently received an ablative dose of iodine-131. After a disease-free interval of about 2 years, she presented with evidence of recurrence in the thyroid bed. She had enlarged cervical lymph nodes and complained of dyspnea on exertion.
Managing chronic sinusitis: Is 3 weeks of antibiotics enough?
February 1st 2007In the treatment of chronic rhinosinusitis, antibiotics are often given for 3 to 6 weeks, but the optimal regimen has not been established. Dubin and coworkers conducted a study to assess the effectiveness of a 3-week course. They found that for some patients, significant radiographic improvement occurs when antibiotics are given for more than 3 weeks.
Acute Glomerulonephritis in a Young Woman
February 1st 2007A 26-year-old woman presented with a1-week history of pleuritic chest painand abdominal pain, which was associatedwith nausea but unrelated tofood intake or bowel movements. Shehad also had gross hematuria for thepast 10 days and swelling around hereyes and ankles as well as fatigue andarthralgias for 2 weeks.
Early Referral for Chronic Kidney Disease: The "Why" and the "How"
February 1st 2007In his recent editorial Putting Guidelines for Chronic Kidney Disease IntoPractice (CONSULTANT, October 2006, page 1295), Dr Gregory Ruteckidiscussed the results of a study that shows many clinicians fail to follow evidence-based guidelines for the management of chronic kidney disease(CKD), such as when to consult a nephrologist.1 A sampling of the feedbackwe received appears below, along with Dr Rutecki's responses.
Kidney Stones: Better to Crush, Capture, or Write a Prescription?
February 1st 2007Medical technology is a double-edged sword. CT scans help detect early disease, but with the addition of contrast, they may cause renal failure. Pacemakers save countless lives, but they can become infected and lead to serious complications.
Colorectal Cancer Screening: Which Tests, How Often?
February 1st 2007ABSTRACT: Screening options for colorectal cancer (CRC) include colonoscopy every 10 years, annual fecal occult blood testing, flexible sigmoidoscopy every 5 years, or double contrast barium enema every 5 years. In white patients at average risk, screening should begin at age 50; in African American patients, at age 45. Colonoscopy is preferred to sigmoidoscopy because it can detect proximal neoplasms and has the longest protection interval. High-risk patients include those with a family history of CRC or adenomas. These persons should begin colonoscopic screening at age 40, or 10 years earlier than the age at which CRC or adenomas were diagnosed in a first-degree relative. Other high-risk patients are those with a personal history of CRC, a genetic syndrome, or inflammatory bowel disease. In patients with CRC, the first follow-up colonoscopy is performed 1 year after surgery. If results are normal, the interval can be extended to every 3 years.
Jejunal Metastasis From Adenocarcinoma of the Lung
February 1st 2007A 59-year-old woman was evaluated for epigastric discomfort and iron deficiency anemia of 2 months' duration. Two years earlier, she had undergone left upper lung lobectomy and adjuvant radiation for T2 N0 M0 poorly differentiated adenocarcinoma of the lung.
STS: Advantage of Stents Over CABG Fizzles in 'Real World'
January 30th 2007SAN DIEGO -- Real-world revascularization outcomes pan out better with coronary artery bypass graft (CABG) than with percutaneous coronary intervention (PCI), even when drug-eluting stents are used, investigators reported here.
ASCO GI: Adjuvant Chemotherapy Plus Chemoradiation May Improve Pancreatic Cancer Survival
January 29th 2007ORLANDO -- Gemzar (gemcitabine) plus Eloxatin (oxaliplatin) adjuvant chemotherapy, followed by chemoradiation ,can improve one-year post-resection recurrence-free survival in pancreatic cancer, suggests a small French study.