NEW YORK ? The American Association of Clinical Endocrinologists (AACE) has enlisted a fitness coach and TV personality for a new campaign aimed at challenging patients with type 2 diabetes to get their blood sugar under control.

NASHVILLE, Tenn. ? Infants whose mothers used ACE-inhibitors during the first trimester are 2.7 times more likely to have major congenital malformations of the cardiovascular and central nervous systems, according to researchers here.

BOSTON ? Carbohydrate nutrition in older nondiabetic persons is related to the development of nuclear and cortical lens opacities, according to a study.

SAPPORO, Japan - Adding whole-brain irradiation to stereotactic radiosurgery does not improve survival of patients with metastatic brain cancer, but it may reduce recurrence of the metastases, researchers here reported.

LIVERMORE, Calif. - As healthy men age, they become less likely to father a successful pregnancy. They have an increased risk for having children with musculoskeletal and craniofacial mutations.

TORONTO ? Second-hand smoke can boost the risk of osteoporosis in pre-menopausal women, researchers reported here.

NEW YORK ? The number of children and adolescents being treated with second-generation antipsychotics, not approved for pediatric patients, has increased steadily in almost a decade, according to national data.

TORONTO ? The concept of calcium and vitamin D supplementation for prevention of osteoporosis, relegated recently to the realm of unfounded notion, got a spirited defense here.

NEW HAVEN, Conn. - Patients with ST-segment elevation myocardial infarction (STEMI) treated with angioplasty within 90 minutes of arriving at the hospital stand a much better chance of being discharged alive, no matter how long it's been since their symptoms started.

ANN ARBOR, Mich. ? A diagnosis of autism in a two-year old, when made by a trained clinician and backed by parent interviews and observation, has a fairly high degree of accuracy, investigators here reported.

ATLANTA ? Adding Avastin (bevacizumab) to either standard chemotherapy or Tarceva (erlotinib) may improve progression-free survival in advanced non-small-cell-lung cancer (NSCLC), according to a phase II study reported here today.

PHILADELPHIA ? As anticipated, young children were better protected from death in car crashes by child safety seats than by seat belts, according to researchers here.

AARHUS, Denmark ? Children born prematurely and those born at term but with low birth weights have an increased risk of developing so-called hyperkinetic disorder, according to researchers here.

BOSTON - A cascade of untoward events can ensue from a false-positive result on newborn screening for genetic disorders, particularly if the parents are not properly briefed by a clinician.

STOCKHOLM – A protein produced by urinary tract epithelial cells, which appears within minutes of the onset of a urinary tract infection, seems to have potent antimicrobial effects.

ATLANTA ? Switching to Aromasin (exemestane), an aromatase inhibitor, as adjuvant therapy for breast cancer after two to three years of tamoxifen may increase disease-free survival, according to mature results of a trial of postmenopausal women.

ATLANTA ? Sutent (sunitinib), a tyrosine kinase inhibitor approved for the treatment of advanced renal cell carcinoma and refractory gastrointestinal stromal tumor (GIST), has also hinted at efficacy for recurrent non-small-cell lung cancer (NSCLC).

ATLANTA ? With a new class of drugs, researchers are on the trail of killer receptors on the surface of cancer cells.

ATLANTA ? Five years of breast cancer adjuvant therapy with an aromatase inhibitor, can lead to a 6% to 7% loss of bone mineral density, a trigger for osteoporosis for women who are borderline osteopenic when they begin treatment, investigators reported here.

ATLANTA ? Many patients with early-stage non-small-cell lung cancer (NSCLC) never see a medical oncologist because their primary care physicians don't think chemotherapy can help them, according to survey results reported here.