Factitious Purpura
This 3-year-old girl was brought to the physician’s office for evaluation of a nonpruritic,purple discoloration around her mouth. The patient’s mother reportedthat the rash developed after the child had eaten a mango and sucked on a cup.
This 3-year-old girl was brought to the physician's office for evaluation of a nonpruritic,purple discoloration around her mouth. The patient's mother reportedthat the rash developed after the child had eaten a mango and sucked on a cup.The eruption in the circumoral area was diagnosed as a factitious purpura.The discoloration was caused by sucking on a cup, which created a negativepressure around the mouth that resulted in the circumoral purpura. The mangoplayed no part in the patient's condition. No treatment was given for the purpura,which resolved on its own. (Case and photograph courtesy of Drs Alexander K. C. Leung and C. Pion Kao.)
Topical PDE4 Inhibitor ZORYVE® (Roflumilast) Cream for the Treatment of Atopic Dermatitis
May 7th 2025ZORYVE® (roflumilast) cream 0.15% is a once-daily, steroid-free PDE4 inhibitor approved for the treatment of mild to moderate atopic dermatitis in patients aged 6 and older. Clinical trials demonstrate its rapid onset, strong efficacy, and favorable safety profile, with emerging evidence supporting its use in younger children and as a long-term maintenance therapy to prevent flares.
