Statin-eligible patients in minority groups significantly undertreated; metabolically healthy obesity on the rise; menstruation irregularities suggest later CVD risk; and 2 more studies of note.
"Even as female reproductive factors are gaining research attention for their potential role in future CV risk, menstrual cycle characteristics have not been included in those investigations and are an underrecognized contributor to adverse CV outcomes in women. The study findings support calls for menstrual cycle history to be included as an additional vital sign when assessing young women’s overall health status."
“These results highlight the need for effective strategies to optimize metabolic status and prevent obesity-related complications among people with obesity, especially among vulnerable subpopulations. Priority should be placed on reinforcing glucose management and reducing insulin resistance among individuals with obesity.”
"The findings in this study indicate that racial and ethnic disparities in the use of statins for primary prevention across all strata of ASCVD risk are associated with poor access to care among individuals of self-reported Black and Hispanic race and ethnicity. They demonstrate the persistent racial and ethnic disparities in guideline-recommended statin use among at-risk adults and represent an opportunity to advance pharmacoequity in primary prevention."
"Echinocandins are a class of antifungals widely used to treat invasive candidiasis, primarily indicated for critically ill and neutropenic patients. Concerningly, this report found that the number of C auris cases with echinocandins resistance in 2021 had tripled in each of the preceding 2 years. Both the rise in antifungal resistance and evidence of transmission are particularly alarming."
"Concussion treatment today includes physical therapy, speech therapy, occupational and vision therapy--a long way from the "wait and see" approach that included rest in a darkened room. Of course, the nature and duration of acute care will differ by individual, but Carneiro says that the approach to recovery from concussion more closely follows the proactive path of treatment for moderate to severe brain injury, drawing from a range of therapeutic modalities that would not have been considered before."