ADA: Metabolic Syndrome Helps Predict Mortality Risk

June 26, 2007

CHICAGO -- Metabolic syndrome and its components helped predict mortality for diabetic and non-diabetic patients alike, independently of Framingham cardiovascular risk, researchers found.

CHICAGO, June 26 -- Metabolic syndrome and its components helped predict mortality for diabetic and non-diabetic patients alike, independently of Framingham cardiovascular risk, researchers found.

In a large study of patients at a preventive cardiology clinic, metabolic syndrome was associated with 53% higher mortality risk than seen among patients who did not have diabetes or metabolic syndrome, said Krupa B. Doshi, M.D., of the Cleveland Clinic, and colleagues.

Fasting plasma glucose and waist circumference-components of metabolic syndrome-were significant predictors of mortality risk in an analysis that adjusted for Framingham score and other factors (P

Mortality rates were highest for patients with diabetes (hazard ratio 2.97, 95% confidence interval 2.33 to 3.79, P