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Androgen receptor gene
1. Giovannucci E, Stampfer MJ, Krithivas K, et al. The CAG repeat within the androgen receptor gene and its relationship to prostate cancer. Proc Natl Acad Sci USA 1997;94(7):3320-3323
Androgen receptor gene (AR)
Stimulated by testosterone. Acts inside prostate to stimulate cell growth. See biological pathway map for further information.
Condition or outcome: Prostate cancer
Variable: Number of CAG repeats in gene (<18 vs >26)
Total of sample sizes in highly cited research:1 1182
Relative risk in highly cited research: 1.23
Relative risk in meta-analysis:2 1.19
Further information from NIH gene database: OMIM entry 313700
1. Giovannucci E, Stampfer MJ, Krithivas K, et al. The CAG repeat within the androgen receptor gene and its relationship to prostate cancer. Proc Natl Acad Sci USA 1997;94(7):3320-3323
2. Edwards SM, Badzioch MD, Minter R, et al. Androgen receptor polymorphisms. Int J Cancer. 1999; 84(5):458-465.
Can Colonoscopy Interval be Safely Extended from 10 to 15 Years for Individuals at Average CRC Risk?
May 3rd 2024New research suggests the interval "could potentially be extended" without significant harms and could reduce unnecessary invasive procedures. , ie, missed early detection and CRC-specific mortality.
