CME Post-Test

June 1, 2005

For each of the following questions, choose the most appropriate answer and record your answer in the space provided on page S11.

For each of the following questions, choose the most appropriate answer and record your answer in the space provided on page S11.

1. Chronic alcohol use results in _________________________ in the activity of glutamate receptors.

a. A decrease

b. A compensatory increase

c. Unpredictable changes

d. None of the above

2. Even in the absence of any treatment, approximately __________ of patients with alcohol dependence will undergo spontaneous long-term remission.

a. 10% to 15%

b. 20% to 30%

c. 40% to 60%

d. None of the above

3. Children of alcoholic parents who exhibit unusually low responses to alcohol have been shown to have rates of alcohol abuse that are _____________________ normal.

a. Higher than

b. Somewhat lower than

c. Markedly lower than

d. Very close to

4. In the Project MATCH study, behavioral therapy using ___________________ produced a significant reduction in the number of days with alcohol consumption.

a. Cognitive-behavioral therapy

b. Motivational enhancement therapy

c. A 12-step program modeled on Alcoholics Anonymous

d. All of the above

5. ________________ does not stop patients from sampling alcohol, but it does reduce episodes of heavy alcohol consumption.

a. Disulfiram

b. Acamprosate

c. Naltrexone

d. None of the above

6. An FDA reanalysis of clinical trial data from European studies found that acamprosate significantly improved:

a. The proportion of patients who remained totally abstinent from alcohol

b. The median number of days to first alcohol use

c. The percentage of days in which patients were abstinent from alcohol

d. All of the above

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