Dermatofibrosarcoma Protuberans
This tumor is a low-grade soft tissue sarcoma. Metastases are uncommon, but local recurrence is very frequent. Mohs surgery is the optimal treatment modality.
A 56-year-old man presented for evaluation of an asymptomatic lesion on the right shoulder. This was discovered accidentally while his wife was giving him a massage.
Key point: There was a subtle 3-cm2 area of thickened nodularity on the shoulder. The lesion was better palpated than visualized. A small punch biopsy revealed this to be dermatofibrosarcoma protuberans.
Treatment: The patient’s tumor was removed easily by Mohs micrographic surgery.
Note: This tumor, often referred to as DFSP, is a low-grade soft tissue sarcoma. While metastases are uncommon (5% to 10%), local recurrence is very frequent. Excision with real-time margin control (eg, Mohs surgery) is the optimal treatment modality. An alternative treatment is simple excision with concomitant wide margin removal (5 cm minimum).
Lebrikizumab Demonstrates Efficacy, Safety in Patients With Skin of Color With AD
June 11th 2025RAD 2025. Lebrikizumab improved skin clearance, itch, and pigmentation in patients with skin of color and atopic dermatitis, with strong safety data through 24 weeks, according to late-breaking data.
