- CDC
- Heart Failure
- Cardiovascular Clinical Consult
- Adult Immunization
- Hepatic Disease
- Rare Disorders
- Pediatric Immunization
- Implementing The Topcon Ocular Telehealth Platform
- Weight Management
- Monkeypox
- Guidelines
- Men's Health
- Psychiatry
- Allergy
- Nutrition
- Women's Health
- Cardiology
- Substance Use
- Pediatrics
- Kidney Disease
- Genetics
- Complimentary & Alternative Medicine
- Dermatology
- Endocrinology
- Oral Medicine
- Otorhinolaryngologic Diseases
- Pain
- Gastrointestinal Disorders
- Geriatrics
- Infection
- Musculoskeletal Disorders
- Obesity
- Rheumatology
- Technology
- Cancer
- Nephrology
- Anemia
- Neurology
- Pulmonology
Leukemia Cutis
A 67-year-old woman noted the appearance of several non-tender, rock-hard, purple-colored nodules on her legs. Her past medical history was significant for distant non-Hodgkin lymphoma.
A 67-year-old woman noted the appearance of several non-tender, rock-hard, purple-colored nodules on her legs. Her past medical history was significant for distant non-Hodgkin lymphoma.
Key point: The violaceous color and configuration of the skin lesions suggests 3 things: mycobacterial infection, cutaneous lymphoma, and leukemia cutis. A biopsy revealed dense aggregates of immature leukocytes (blasts), suggesting an aggressive leukemia. Bone marrow aspiration was confirmatory.
Treatment: The patient is undergoing chemotherapy at the direction of a hematological oncologist.
Note: Once leukemia involves the skin, the prognosis is often quite grave. The most common cause of leg nodules, erythema nodosum, is expected to be painful.
