Mayo Clinic Researcher on Why Menopause Stage Matters in Metabolic Research

Understanding how menopause influences metabolic health is critical for clinicians working with midlife and older women. In this segment, Regina Castaneda, MD, discusses why reproductive stage should be considered a key variable in weight-management and obesity-pharmacotherapy research. She explains how the transition into menopause increases cardiometabolic risk, how obesity compounds this risk, and why many postmenopausal patients worry they may respond differently to weight-loss medications. Castaneda highlights the importance of answering these questions to guide personalized treatment strategies for millions of women navigating this stage of life.