It is often surprising how wide and how deep skin cancers have already spread, despite a relatively small-looking superficial component. This patient had a history of melanoma in situ.
A 58-year-old man presented with the new onset of an asymptomatic papule on the left upper arm. His past medical history included a melanoma in situ, several basal cell carcinomas, and many actinic keratoses.
Key point: Although the lesion was only about 2.5 mm in greatest diameter, it was surmounted by a rough keratin scale and felt firm to the touch. Biopsy revealed a moderately well-differentiated squamous cell carcinoma invading the subcutaneous fat.
Treatment: Moh’s surgery was performed; the final defect remaining after obtaining tumor-free margins was 2.6 cm, consistent with an aggressive neoplasm.
Note: It is often surprising how wide and how deep skin cancers have already spread, despite a relatively small-looking superficial component.
Biden Administration Announces First 10 Prescription Drugs Slated for Price Negotiations
August 29th 2023The first 10 drugs identified for negotiations under the Inflation Reduction Act include several well advertised agents indicated to treat diabetes, heart failure, and other chronic diseases.