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A video series from James Mohler of Rosweel Park Cancer Institute on PSA testing in the wake of changing guidelines from the US Preventive Task Force.

Commentary on the USPF's Recommendations on PSA Testing

A 67-year-old woman noted the appearance of several non-tender, rock-hard, purple-colored nodules on her legs. Her medical history was significant for distant non-Hodgkin lymphoma.

A 67-year-old woman noted the appearance of several non-tender, rock-hard, purple-colored nodules on her legs. Her medical history was significant for distant non-Hodgkin lymphoma. The violaceous color and configuration of the skin lesions suggests which of the following? 

Clinical Topics

Hard Purple Nodules: Your Dx?

A 76-year-old woman seeks your attention for an asymptomatic “red spot” on her neck. She has a history of multiple non-melanoma skin cancers.

Squamous cell carcinoma in situ (Bowen  disease)

Lichenoid keratosis (an inflammatory variant of seborrheic keratosis)

A 76-year-old woman seeks your attention for an asymptomatic “red spot” on her neck. What does this look like to you?

What's This "Red Spot"?

The patient, a 60-year-old black woman, presented with muscle weakness, Raynaud phenomenon, joint pain, and discoloration of her hands. She had proximal muscle weakness and mild synovitis in her metacarpophalangeal joints. Autoantibody tests were positive for ANA antibodies and anti-Jo1 antibodies and negative for anti–double-stranded DNA, anti-Smith, anti-U1-RNP, anti-SSA, anti-SSB, HIV, and hepatitis C virus antibodies.

(Photo credit: Michael Guma, DO and Daphne Macbruce, MD)
 

What condition is represented by inflammatory muscle disease, interstitial lung disease, Raynaud phenomenon, arthritis, and cutaneous manifestations, and in what rheumatologic diseases might you see it? 

Pigment Changes and Muscle Weakness 

A 9-year-old boy presented with a 1-week history of pruritus and rash on his elbows, knees, back, and legs. Several areas of excoriation were noted. He had recently run through a field of tall grass but denied any other exposure history.

A 9-year-old boy presented with a 1-week history of pruritus and rash on his elbows, knees, back, and legs. He had recently run through a field of tall grass but denied any other exposure history. Your Dx?

What Cause of This Itchy Rash?

A 5-year-old boy with a history of atopic dermatitis since 6 weeks of age, presents with a rash around his mouth that has been present for approximately 1 year. The patient’s mother reports that desonide topical cream was applied to the affected area for about 5 days, which initially resulted in improvement, however the rash returned after this medication was discontinued. The rash also recently improved after the patient took amoxicillin for an infection. She also notes that the patient has been licking his lips more frequently.

On examination there is an erythematous papulopustular eruption restricted to the perioral region, with sparing of the vermillion border. Mild hyperpigmentation is noted on the patient’s neck. There is no active involvement of other areas of the body.

The eruption has been present for 1 year and is restricted to the perioral region. What is included in your differential? 

Rash Around the Mouth of a 5-year-old Child

Explore essential strategies to manage your infusion center's finances effectively with our guide. Learn to navigate high medication costs, optimize cash flow, and discover the best financing options suited to your needs. Whether you're battling lengthy reimbursement cycles or seeking to improve overall financial health, this guide provides actionable insights to maintain and grow your center sustainably.

Unlock Optimal Cash Flow and Financing Solutions for Your Infusion Center

James L. Mohler, MD

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