Heart Failure

Cardiovascular Clinical Consult

Adult Immunization

Hepatic Disease 

Behcet’s Disease

Rare Disorders

Pediatric Immunization

Implementing The Topcon Ocular Telehealth Platform

Weight Management

Screening

Monkeypox

Guidelines

Men's Health

Panic Disorder  

Anxiety

Eating Disorders

Depression

Substance-related Disorders

ADHD

Psychiatry 

Seasonal Allergies

Allergy

Nutrition 

Pregnancy and Birth

Women's Health

Atrial Fibrillation

Cholesterol Disorders

Cardiovascular Disease

Hypertension

Cardiology

Substance Use

Child/Adolescent

Pediatrics

Kidney Disease

Genetics

Medical Cannabis

Complimentary & Alternative Medicine

Skin Diseases

Dermatology

Thyroid Disorders 

Diabetes

Diabetes Type 2

Insulin

Endocrinology 

Oral Medicine 

Otorhinolaryngologic Diseases

Fibromyalgia

Pain

Irritable Bowel Syndrome 

Inflammatory Bowel Disease

Gastrointestinal Disorders

Geriatrics

Coronavirus

Hepatitis C

Cold, Cough, and Flu

Bacterial Conjunctivitis

Immunization

Influenza

HIV AIDS

Sexually Transmitted Diseases

Infection

Osteoporosis

Imaging 

Musculoskeletal Disorders  

Obesity

Rheumatoid Arthritis

Arthritis

Gout

Rheumatology

Technology

Colorectal Cancer

Kidney Cancer

Lung Cancer

Melanoma

Skin cancer

Prostate Cancer

Breast Cancer

Cervical Cancer

Cancer

Nephrology

Anemia

Dementia

Epilepsy

Cerebrovascular Diseases

Headache and Migraine

Parkinson Disease

Alzheimer disease

Stroke

Mental Health

Headache

Migraine

Nervous System Diseases

Sleep Disorders

Neurology

Asthma

Cystic Fibrosis

COPD

Pneumonia

Respiratory Diseases

Pulmonology

News

All News

Office Procedures

Practice Management

Media

Around the Practice

Between the Lines

ConsultantLive

Expert Interviews

Frontline Insights

Institutional Insights

Medical World News

Podcasts

Primary View

Provider Toolkits

Readout360

Conferences

Conference Coverage

Conference Listing

Resources

Image IQ

Interactive Posters

Polls

Publications

Quizzes

Subscribe

CE/CME

Advertise

Contact Us

Terms and Conditions

Privacy

Do Not Sell My Information

Patient Care Online

Facebook

LinkedIn

Clinical Focus

Allergy & Immunology

Endocrinology

Gastroenterology

Infectious Disease

Men’s Health

Pain Management

Psychiatry

Women’s Health

Business Focus

Billing and Collections

Career Planning

Coding and Documentation

Concierge Medicine

Cybersecurity

EHRs

Investing

Patient Relations

Personal Finance

Remote Patient Monitoring

Staffing

Telehealth

Value-based Care

Spotlight

Unmet Needs in Managing MDD

Interpreting Thyroid Function Tests

Using Thyroid Lab Tests

Testing & Screening to Optimize Men's Health

1rem

Authors

The authors present a case of rupture of the rectus abdominis muscle with subsequent rectus sheath hematoma-an uncommon and often misdiagnosed cause of acute abdominal pain. 

Rectus Sheath Rupture With Hematoma Formation

A 29-year-old man presented with a 4-year history of headache and severe neck pain. He denied weakness, ataxia, radicular symptoms, and loss of bladder or bowel control.

A 29-year-old man presented with a 4-year history of headache and severe neck pain. What does the cervical MRI scan without contrast reveal?

Clinical Topics

Constant Headache and Neck Pain

Key Insights and Final Thoughts on Screening and Management of T1D

The following Frontline Insights transcript has been edited for clarity and length.


 I want to ask the audience, did you find this discussion helpful in understanding type 1 diabetes staging and management?

 While the audience is responding, I’d like to share that at our pediatric center, we've made the decision to conduct all infusions, including on weekends, in our infusion center. We've managed to staff it appropriately, so if there’s anyone in the Dallas area in need of these services, please don’t hesitate to refer them to us.

 Absolutely, it's important to spread the word, and we’re all in this together to support our community. It seems that most of our audience found this discussion quite insightful. Now, I have another question for our viewers: What was the key takeaway regarding type 1 diabetes staging and management? Please select all that apply. Was it:

Acknowledging the staged progression of type 1 diabetes?

Identifying the appropriate referral pathways for type 1 diabetes staging?

Understanding the importance of recognizing high-risk patient populations?

Recognizing the role of antibody testing in assessing type 1 diabetes progression?

Gaining insight into the ability to delay the diagnosis or progression of type 1 diabetes?

And it looks like 100% of you selected the ability to delay the progression of type 1 diabetes. Bravo to everyone, as that was our main message. It’s also encouraging that most of you selected all the choices, except for identifying the appropriate referral pathways for type 1 diabetes staging. This is a key point—recognizing the disorder, screening for it, and knowing the next steps if you get a positive result.

To close, I’d like to ask our presenters to share a few final thoughts. From my perspective, I learned a lot about screening, the relevant antibodies to use, and the proper course of action when you receive a positive test result. Natalie, would you like to share your closing thoughts?

Natalie Bellini, DNP, FNP-BC, BC-ADM, CDCES: 

I think we need to fully embrace the idea that screening can save lives and reduce the risks of DKA. We should make screening a routine part of patient history. Ask questions like, "Do you have siblings? Do they have diabetes? What kind of diabetes do they have? Do they take insulin?" If the answer is yes, start screening these individuals. Partner with an endocrinology practice to support you, and don’t hesitate to ask for help. I’ve never encountered a practice that’s unwilling to help—there are always spots available for those who screen positive.

Aubrey Molgaard, DNP, ARNP, FNP-BC, CDCES: 

I completely agree with Natalie. I work with adults, and we have spots available every day. When someone identifies as at risk, we get them in quickly. It's life-changing, and we can make a significant impact on disease progression. Screening is essential. Collaborate with us—we're here to help and partner with you.

 Finally, Abha, do you have any final words?

 Once a patient enters the early stages of diabetes, whether stage one or stage two, progression to stage three is inevitable. So, screen it like you mean it! If you find antibodies, send them over to us—we have appointments available in our pediatric clinic. We will see your patients quickly. Thank you.

 "Screen it like you mean it!" I love that. It’s not just a great catchphrase; it’s a reminder that screening is crucial—not only for type 1 diabetes but for many other chronic conditions. Thank you all for your attention and for engaging in this discussion. We hope you’ve learned more about how we can delay the progression of type 1 diabetes in stage two. Stay tuned for more episodes, and have a wonderful evening. And remember, screen it like you mean it.

Panelists discuss key insights on the importance of early screening for T1D, the role of antibody testing in identifying at-risk individuals, and the need for timely intervention to preserve ß-cell function and optimize long-term management strategies for better patient outcomes.

Video Series

Teplizumab for Delaying Onset and Progression of T1D

The following Frontline Insights transcript has been edited for clarity and length.

Let’s pose a question to the audience: Are you aware of any medical facilities in your area that offer teplizumab infusions? Please choose the most accurate response.

Abha, teplizumab is a relatively new treatment, and setting up infusion facilities and protocols must be challenging. While some infrastructure likely exists, building and expanding these networks must require significant effort. From our audience responses, it seems that about three-quarters are unaware of such facilities, while a smaller portion has some familiarity.

Dr. Molgaard, can you describe how your facility has implemented protocols for teplizumab infusions?

Aubrey Molgaard, DNP, ARNP, FNP-BC, CDCES

: Developing our protocol took about a year. We now have an outpatient infusion center accessible across the United States through our healthcare system. We also offer hybrid models, including home infusions, which expand patient options. These protocols are in place for both adult and pediatric patients, ensuring a safe and well-managed process.

Panelists discuss how teplizumab, an anti-CD3 monoclonal antibody, delays the onset and progression of type 1 diabetes by modulating immune response and preserving ß-cell function in high-risk individuals.

Katherine P. Trayes, MD

Articles

Latest Updated Articles