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How Doctors Can Win the Vaccine Debate With PatientsParental fears and misinformation about vaccines can be overcome, says this expert. Here are some suggestions.
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Adult and Adolescent Immunizations: When to Recommend the New VaccinesVaccination rates in adults are lower than those in children, but the consequences of lack of immunization in adults are just as significant. Barriers to adult immunization include patients’ lack of knowledge or misconceptions about vaccines and health care providers’ failure to recommend vaccination.1
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Erectile Dysfunction:ABSTRACT: The number of medical therapies for patients with erectile dysfunction (ED) has increased in recent years because of our expanded understanding of the physiologic and neurologic causes of ED. Oral agents range from testosterone to antidepressants to phosphodiesterase inhibitors. Nitroglycerin and minoxidil have shown some effectiveness as topical agents. Alprostadil, which can be applied intraurethrally, is also effective as intracavernosal injection therapy. Prostaglandin E1 and papaverine are effective as intracavernosal injection agents. Some studies have shown that combined use of intracavernosal injection and oral therapy produces satisfactory erections.
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CNS LipomaA 62-year-old African American woman was brought to the emergency department (ED) after the sudden onset of slurred speech and weakness in her left arm and leg. Her medical history included hypertension, insulin-dependent diabetes, and congestive heart failure.
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Mediastinal Benign SchwannomaThe mediastinal benign schwannomas is a nerve sheath tumor composed of Schwann cells. These tumors are often asymptomatic and found incidentally.
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“Tear Out” Sheets for Quick ReferenceAlthough topical corticosteroid therapy can be highly effective, such treatment can be costly-especially whenbrand-name products are prescribed for extensive or chronic conditions. Here we describe an economical approachthat does not sacrifice either efficacy or safety.
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Post-Test on Obesity in Primary CareTake this brief quiz to see what you’ve learned about the challenges and opportunities of obesity management.
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Clinical Consultation: Risk of anaphylactoid reactions to COX-2 inhibitorsSelective cyclooxygenase-2 (COX-2) inhibitors, such as celecoxib, rofecoxib, and valdecoxib, are an effective and commonly used class of drugs for the management of pain. They are particularly useful in patients who are unable to tolerate aspirin or traditional NSAIDs because of side effects.
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Strategies for preventing the common cold: The current evidenceAlthough the common cold is usually benign, it can lead to exacerbations of asthma and chronic obstructive pulmonary disease, and it is a leading cause of missed school and work. Strategies for prevention have been directed at interruption of viral transmission between persons, as with the use of virucidal agents or disinfectants, and prevention of infection after acquisition of the pathogen. Hand washing continues to be recommended, but there is no proof that hand sanitizers or virucidal tissues are effective in preventing colds. Prophylactic therapies that have been considered include vitamin C, vitamin E, zinc, Echinacea, ginseng, and probiotics. Although some evidence may suggest possible benefits with zinc and probiotics, for example, overall, the data are insufficient to recommend any of these as prophylaxis for the common cold. (J Respir Dis. 2009;30)
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Bedbug Bites in a 34-Year-Old WomanA 34-year-old woman presented with a blistering, intensely pruritic rash that had erupted 3 days earlier. Multiple papular lesions were densely clustered on areas of exposed skin. Excoriations were present, but there was no evidence of bacterial infection.
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Herbal Medicine:An examination the most recent data on the pharmacodynamics, efficacy, and safety of 5 commonly used herbs: echinacea, St John's wort, ginkgo biloba, saw palmetto, and black cohosh.
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Middle-Aged Man With Severe Upper Back and Neck PainFor 4 weeks, a 49-year-old man has had progressively worsening pain between his scapulae and in the lower part of his neck. The pain is now severe, and he takes high doses of acetaminophen and NSAIDs for relief.
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Benign Familial Chronic PemphigusFor 6 years, a 32-year-old man had a recurring rash on his back, shoulders, and chest. He stated that the rash appears in the spring, itches, and enlarges into ringlike areas. Previously, when treated with cephalexin, the rash had cleared within several weeks. Antifungal medication (econazole cream and oral terbinafine) had failed to resolve the rash.
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GI Distress in a Middle-Aged WomanFor several months, a 52-year-old woman has had burning discomfort in the region of her lower sternum and frequent acid/sour sensations in her throat; the symptoms are usually associated with burping after meals and recumbency.
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Acute lymphoblastic leukemia presenting with an acute fibrinous and organizing pneumoniaThe authors report a case of adult-onset acute lymphoblastic leukemia (ALL) presenting with a right upper lobe infiltrate associated with acute fibrinous and organizing pneumonia (AFOP), which resolved spontaneously during the course of chemotherapy.
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Postoperative complications in patients with OSATo what extent are patients with obstructive sleep apnea syndrome (OSAS) at increased risk for postoperative complications? Are there any specific interventions that reduce the risks?
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Combating Allergens at Home: What You Need to Know About Preventing AsthmaIf you suffer from allergies or asthma, there are a variety of things you can do inside your home to limit your exposure to allergens that can cause asthma or make it worse.
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Case In Point: Exfoliative dermatitis: A presenting sign of lung cancerA 53-year-old man presented with a 3-day history of bilateral pain in the lower extremities. He also had a 3-month history of thickening and desquamation of skin, with associated itching, and a 5-lb (2.27-kg) weight loss. The skin changes initially appeared on the hands and subsequently became generalized.
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Emphysematous Pyelonephritis Caused by Pasteurella multocidaEmphysematous pyelonephritis (EPN) is a rare but life-threatening infection characterized by widespread necrosis and production of gas within the kidney.
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Pap Smears: A Method for Giving Patients ResultsWhen patients come in for a Pap smear, we have them write their name and address on an envelope, which we file in a box organized by month. Then as results come in, we retrieve the appropriate envelopes from the box and mail them out. Any envelopes left in the folder at the end of the month serve as reminders that those patients haven't been contacted yet.
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Spontaneous Lung Herniation, Acute Cough, and PneumoniaThe patient described here was treated for pneumonia, but a chest wall mass and CT changes suggested that more was going on.
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Update on Cause and Management of Catscratch DiseaseMore than 22,000 persons in the United States are affected bycatscratch disease (CSD) annually. Despite the discovery of thecausative organism more than a decade ago, much is still unknownabout this illness. Recent data suggest that ticks, as wellas cats, may transmit the disease to humans. Immunofluorescenceassay is proving to be the most efficient and noninvasivetechnique for diagnosing CSD. Among available antimicrobials,azithromycin has proved to be especially useful, although randomized,double-blind, placebo-controlled trials are warrantedto define the best treatment method for patients with CSD.[Infect Med. 2008;25:242-246, 250]
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Clostridium difficile: Which Test to Order and How Often?Which test should you order if you suspect Clostridium difficile infection-and how often do you check the stool for the C difficile toxin? Here: the answer-and explanation.
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Papillary Carcinoma of the ThyroidA 40-year-old man was concerned about an enlarging painless mass on the right side of his neck that had been present for 6 months. The patient reported no other health problems; his medical history was unremarkable, and he was taking no medications.
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Serum Digoxin Concentrations: Do You Know the Current Upper Limit in Heart Failure?For more than 30 years, serumdigoxin concentrations (SDCs)have been monitored toensure safe, effective therapy.1,2Although the therapeuticrange for SDCs is often listed as either0.8 to 2.0 ng/mL or 0.5 to 2.0ng/mL, the results of clinical trials inthe 1990s suggest an upper limit of1.0 ng/mL for treatment of heart failure.3-11 An upper limit for the SDC of1.0 ng/mL is also recommendedfor patients who have heart failureand atrial fibrillation with rapid ventricularresponse.
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A covert cause of hypoxemia: Intravascular pulmonary lymphomaWe describe a patient with intravascularpulmonary lymphomawho presented withprogressive dyspnea and hypoxemiawith normal chest radiographicfindings. After anunrevealing noninvasive evaluation,a high-grade B-cellintravascular lymphoma wasdiagnosed by bronchoscopywith transbronchial biopsy.Treatment with a modifiedCHOP regimen resulted in resolutionof the patient’s hypoxemiaand exercise limitation.Although intravascular pulmonarylymphoma rarely presentswith pulmonary symptoms,it should be consideredin the differential diagnosis ofpatients presenting with hypoxemiaand normal chest radiographicfindings.
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Diagnostic Nucleic Acid Testing for Invasive Fungal InfectionsOver the past 2 decades, there has been an alarming increase in opportunistic fungal infections with an associated rise in morbidity and mortality. This trend has been attributed to the growing number of patients who are immunocompromised because of bone marrow or solid organ transplant, immunosuppressive drugs, AIDS, and hematological malignancies. Advances in trauma and critical care medicine that lead to longer survival of more patients with immunocompromising conditions also play a role.
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FilariasisA 16-year-old boy was evaluated for elephantiasis in a remote village in the mountains of Kenya. He complained of drainage from his left leg and reported that for the past several months, after the limb swelled, fluid began to weep from the bottom of the foot. He denied pain in his leg or foot and reported no fever, chills, or sweats.
