Endocrinology

A new study examines the legacy effects of weight loss on cardiometabolic disease risk factors, finding benefits persist up to 5 years, despite weight regain.

The disproportionate prevalence of undiagnosed diabetes among racial/ethnic minorities in the US begs for a new screening paradigm; this may be the one.

Sanofi is the third key insulin maker to announce reductions in the cost of its products, joining other giants Eli Lilly and Co and Novo Nordisk.

The announcement follows by 2 weeks a similar plan from Eli Lilly to reduce patient costs as the Biden administration touts effects of new laws on drug prices.

Young children using a hybrid closed-loop insulin delivery system spent 12% more time within their target blood glucose range than those who received standard care, according to new research.

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ACC2023. For high-risk T2D patients not receiving optimal treatment for hyperlipidemia, hypertension, or hyperglycemia, intensive, multidisciplinary training for clinic staff could shift practice.

Some of the insulin price cuts announced will be effective immediately, others will roll out in April and May; Lilly Chair and CEO calls industry and lawmakers to join the effort.

ACC 2023. New study found cognitive behavioral therapy delivered via mobile app significantly reduced HbA1c and need for antihyperglycemic intensification compared to use of a control app.

Many older adults show symptoms of food addiction, a new survey found. Is it time to start screening? A primary care physician considers the feasibility and the value.

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The magnitude of the association with age did not change, however, for other stroke risk factors, including smoking, atrial fibrillation, and LVH, investigators report.

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Women who gave birth to infants in the highest birthweight category were at a 21% increased risk for prediabetes/diabetes 10 to 14 years later.

The proportion of adults with diabetes and obesity in the US increased from 1999 to 2020, though more adults achieved blood pressure and lipid control during the same period.

The beneficial effects of SGLT-2 inhibitors in reducing CV death and heart failure hospitalization in patients with T2D are related to body weight, suggest new data.

The 6 obesity care organizations are collaborating to overcome the roadblocks to effective and equitable treatment for the ubiquitous, chronic, and deadly disease.

Risk of T2D was reduced by 49% over a 10-year follow up period among study participants who followed a vigorous or moderate exercise plan vs those who did not engage in exercise.

The DASH diet, Mediterranean diet, and Flexitarian diet top the list of 10 best diets for persons with diabetes as ranked by US News and World Report.

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Sustained weight loss with semaglutide 2.4 mg is a result of the drug's effects on control of eating, including reduced cravings and hunger and increased satiety, study authors write.

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Bexagliflozin significantly improved glycemic control in adults when used as monotherapy, in combination with metformin, or when added to several SOC regimens.

Adults with T2D may be able to reduce their liver fat and improve their liver fibrosis stage with reductions in HbA1c, according to findings from a retrospective analysis.

Investigators report a 30% reduced risk of total joint replacement in persons with type 2 diabetes treated with metformin vs those who did not receive the drug.

An overall good quality of diet and higher fish intake during pregnancy were related to better language skills in 2-year-old children, according to new study.

Australian investigators found a 14% higher risk of fracture for every 1-SD increment in level of HDL-C in community dwelling healthy adults aged ≥70 years.

The update removes a previous limitation that stated semaglutide should not be used as an initial therapy for treating patients with T2D.

The 13 Key Action Steps in the AAP's landmark obesity guidelines reflect more than a decade of research on evaluation and treatment of the disease in children and adolescents.